Metabolomics - the new "omics" of health care
Metabolic diseases are caused by chronic dysregulations of metabolism that differ among individuals due to interactions of the genetic and environmental influences manifesting as a particular phenotype. These are usually diagnosed with the help of individual metabolites which serve as disease biom...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-07-01
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| Series: | Journal of Clinical and Scientific Research |
| Subjects: | |
| Online Access: | http://svimstpt.ap.nic.in/jcsr/jul-sep%2012_files/jul-sep%202012/ra1.pdf |
| _version_ | 1798018409593569280 |
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| author | V.S. Kiranmayi P.V.L.N. Srinivasa Rao Aparna R. Bitla |
| author_facet | V.S. Kiranmayi P.V.L.N. Srinivasa Rao Aparna R. Bitla |
| author_sort | V.S. Kiranmayi |
| collection | DOAJ |
| description | Metabolic diseases are caused by chronic dysregulations of metabolism that differ among individuals due to interactions
of the genetic and environmental influences manifesting as a particular phenotype. These are usually diagnosed
with the help of individual metabolites which serve as disease biomarkers. However, single biomarker based diagnostics
for metabolism-based diseases fails to identify the cause of the alteration of these surrogate markers. This is where
metabolomics comes into the clinical picture as it not only helps in assessing the risk of an individual for developing a
particular disease but also helps in individualizing therapy based on the metabolic defect. Metabolomics is named in
line with other recently developed approaches of diagnostics, i.e., genomics and proteomics. This review provides an
overview of the fundamental basic principles, the techniques involved and the applications of this new -omics of
healthcare. |
| first_indexed | 2024-04-11T16:23:40Z |
| format | Article |
| id | doaj.art-aff40f90586f414b8eef221049223d66 |
| institution | Directory Open Access Journal |
| issn | 2277-5706 2277-8357 |
| language | English |
| last_indexed | 2024-04-11T16:23:40Z |
| publishDate | 2012-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical and Scientific Research |
| spelling | doaj.art-aff40f90586f414b8eef221049223d662022-12-22T04:14:16ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Scientific Research2277-57062277-83572012-07-0113131137Metabolomics - the new "omics" of health careV.S. Kiranmayi0P.V.L.N. Srinivasa Rao1Aparna R. Bitla2Department of Biochemistry, Sri Venkateswara Institute of Medical Sciences, TirupatiDepartment of Biochemistry, Sri Venkateswara Institute of Medical Sciences, TirupatiDepartment of Biochemistry, Sri Venkateswara Institute of Medical Sciences, TirupatiMetabolic diseases are caused by chronic dysregulations of metabolism that differ among individuals due to interactions of the genetic and environmental influences manifesting as a particular phenotype. These are usually diagnosed with the help of individual metabolites which serve as disease biomarkers. However, single biomarker based diagnostics for metabolism-based diseases fails to identify the cause of the alteration of these surrogate markers. This is where metabolomics comes into the clinical picture as it not only helps in assessing the risk of an individual for developing a particular disease but also helps in individualizing therapy based on the metabolic defect. Metabolomics is named in line with other recently developed approaches of diagnostics, i.e., genomics and proteomics. This review provides an overview of the fundamental basic principles, the techniques involved and the applications of this new -omics of healthcare.http://svimstpt.ap.nic.in/jcsr/jul-sep%2012_files/jul-sep%202012/ra1.pdfMetabolic disordersMetabolomicsHealth care |
| spellingShingle | V.S. Kiranmayi P.V.L.N. Srinivasa Rao Aparna R. Bitla Metabolomics - the new "omics" of health care Journal of Clinical and Scientific Research Metabolic disorders Metabolomics Health care |
| title | Metabolomics - the new "omics" of health care |
| title_full | Metabolomics - the new "omics" of health care |
| title_fullStr | Metabolomics - the new "omics" of health care |
| title_full_unstemmed | Metabolomics - the new "omics" of health care |
| title_short | Metabolomics - the new "omics" of health care |
| title_sort | metabolomics the new omics of health care |
| topic | Metabolic disorders Metabolomics Health care |
| url | http://svimstpt.ap.nic.in/jcsr/jul-sep%2012_files/jul-sep%202012/ra1.pdf |
| work_keys_str_mv | AT vskiranmayi metabolomicsthenewomicsofhealthcare AT pvlnsrinivasarao metabolomicsthenewomicsofhealthcare AT aparnarbitla metabolomicsthenewomicsofhealthcare |