Primitive neuroectodermal tumor of the penile urethra
Primitive neuroectodermal tumor (PNET)/Ewing's sarcoma tumors are a group of highly malignant tumors composed of small, round cells showing neuroectodermal differentiation that commonly affects soft tissue and bone. PNET involving the genitourinary system is rare and PNET of the penile urethra...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Indian Journal of Urology |
| Online Access: | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2021;volume=37;issue=1;spage=84;epage=86;aulast=Asari |
| _version_ | 1818654917710053376 |
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| author | Ashishkumar Narsinhbhai Asari Bijal Kulkarni T B Yuvaraja |
| author_facet | Ashishkumar Narsinhbhai Asari Bijal Kulkarni T B Yuvaraja |
| author_sort | Ashishkumar Narsinhbhai Asari |
| collection | DOAJ |
| description | Primitive neuroectodermal tumor (PNET)/Ewing's sarcoma tumors are a group of highly malignant tumors composed of small, round cells showing neuroectodermal differentiation that commonly affects soft tissue and bone. PNET involving the genitourinary system is rare and PNET of the penile urethra is rarer still. It exhibits a highly aggressive biological behavior with poor prognosis. We report a case of a 27-year-old male presenting with penile swelling and difficulty in passing urine. Examination revealed a firm penile urethral mass. Pathological and immunohistochemical results of the specimen obtained from urethroscopic biopsy followed by total penectomy confirmed the diagnosis of PNET of the urethra. He received combination chemotherapy: ifosfamide and etoposide (IE) + vincristine, Adriamycin, and cyclophosphamide (VAC). In conclusion, PNET has to be considered in the differential diagnosis of a penile urethral mass in young patients. |
| first_indexed | 2024-12-17T03:01:25Z |
| format | Article |
| id | doaj.art-aff530cb1bf14aaf84d3c9708b7bbea5 |
| institution | Directory Open Access Journal |
| issn | 0970-1591 1998-3824 |
| language | English |
| last_indexed | 2024-12-17T03:01:25Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Urology |
| spelling | doaj.art-aff530cb1bf14aaf84d3c9708b7bbea52022-12-21T22:06:04ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242021-01-01371848610.4103/iju.IJU_178_20Primitive neuroectodermal tumor of the penile urethraAshishkumar Narsinhbhai AsariBijal KulkarniT B YuvarajaPrimitive neuroectodermal tumor (PNET)/Ewing's sarcoma tumors are a group of highly malignant tumors composed of small, round cells showing neuroectodermal differentiation that commonly affects soft tissue and bone. PNET involving the genitourinary system is rare and PNET of the penile urethra is rarer still. It exhibits a highly aggressive biological behavior with poor prognosis. We report a case of a 27-year-old male presenting with penile swelling and difficulty in passing urine. Examination revealed a firm penile urethral mass. Pathological and immunohistochemical results of the specimen obtained from urethroscopic biopsy followed by total penectomy confirmed the diagnosis of PNET of the urethra. He received combination chemotherapy: ifosfamide and etoposide (IE) + vincristine, Adriamycin, and cyclophosphamide (VAC). In conclusion, PNET has to be considered in the differential diagnosis of a penile urethral mass in young patients.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2021;volume=37;issue=1;spage=84;epage=86;aulast=Asari |
| spellingShingle | Ashishkumar Narsinhbhai Asari Bijal Kulkarni T B Yuvaraja Primitive neuroectodermal tumor of the penile urethra Indian Journal of Urology |
| title | Primitive neuroectodermal tumor of the penile urethra |
| title_full | Primitive neuroectodermal tumor of the penile urethra |
| title_fullStr | Primitive neuroectodermal tumor of the penile urethra |
| title_full_unstemmed | Primitive neuroectodermal tumor of the penile urethra |
| title_short | Primitive neuroectodermal tumor of the penile urethra |
| title_sort | primitive neuroectodermal tumor of the penile urethra |
| url | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2021;volume=37;issue=1;spage=84;epage=86;aulast=Asari |
| work_keys_str_mv | AT ashishkumarnarsinhbhaiasari primitiveneuroectodermaltumorofthepenileurethra AT bijalkulkarni primitiveneuroectodermaltumorofthepenileurethra AT tbyuvaraja primitiveneuroectodermaltumorofthepenileurethra |