Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations
The majority of works about vine-canes are focused on the evaluation of their chemical composition and antioxidant potential. To the best of our knowledge, the possible applications of produced extracts in cosmetic formulations have never been explored. The aim of the present study was to evaluate t...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/13/2969 |
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| author | Manuela M. Moreira Francisca Rodrigues Olena Dorosh Diana Pinto Paulo C. Costa Jaroslava Švarc-Gajić Cristina Delerue-Matos |
| author_facet | Manuela M. Moreira Francisca Rodrigues Olena Dorosh Diana Pinto Paulo C. Costa Jaroslava Švarc-Gajić Cristina Delerue-Matos |
| author_sort | Manuela M. Moreira |
| collection | DOAJ |
| description | The majority of works about vine-canes are focused on the evaluation of their chemical composition and antioxidant potential. To the best of our knowledge, the possible applications of produced extracts in cosmetic formulations have never been explored. The aim of the present study was to evaluate the antioxidant properties of vine-canes subcritical water extracts for use as active ingredients in the cosmetic industry. For that, the phenolic content and antioxidant activity of six vine-cane varieties, namely Alvarinho and Loureiro from the Minho region and Touriga Nacional and Tinta Roriz (TR) from both the Douro and Dão regions, were evaluated through spectrophotometric and chromatographic methods. All extracts presented similar antioxidant activity and the highest phenolic content was reported for TR variety from the Douro region (33.7 ± 1.9 mg GAE/g dw). The capacity of vine-cane extracts to capture reactive oxygen species superoxide (O<sub>2</sub><sup>∙−</sup>) was also studied, with the highest IC<sub>50</sub> value being obtained for Loureiro variety (56.68 ± 2.60 µg/mL). Furthermore, no adverse effects on HaCaT and HFF-1 dermal cell lines in concentrations below 100 and 1000 μg/mL, respectively, were determined. Finally, Loureiro vine-cane extract was incorporated into a topical formulation, and physical and microbiological properties were within expected values, demonstrating that vine-canes extracts can be successfully incorporated in cosmetic products. |
| first_indexed | 2024-03-10T18:49:41Z |
| format | Article |
| id | doaj.art-affe1ac8e5764a85880f19871b3c9922 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T18:49:41Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-affe1ac8e5764a85880f19871b3c99222023-11-20T05:13:33ZengMDPI AGMolecules1420-30492020-06-012513296910.3390/molecules25132969Vine-Canes as a Source of Value-Added Compounds for Cosmetic FormulationsManuela M. Moreira0Francisca Rodrigues1Olena Dorosh2Diana Pinto3Paulo C. Costa4Jaroslava Švarc-Gajić5Cristina Delerue-Matos6REQUIMTE/LAQV, Instituto Superior de Engenharia do Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, PortugalREQUIMTE/LAQV, Instituto Superior de Engenharia do Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, PortugalREQUIMTE/LAQV, Instituto Superior de Engenharia do Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, PortugalREQUIMTE/LAQV, Instituto Superior de Engenharia do Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, PortugalREQUIMTE/UCIBIO, MedTech-Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira nº. 228, 4050-313 Porto, PortugalFaculty of Technology, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, SerbiaREQUIMTE/LAQV, Instituto Superior de Engenharia do Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, PortugalThe majority of works about vine-canes are focused on the evaluation of their chemical composition and antioxidant potential. To the best of our knowledge, the possible applications of produced extracts in cosmetic formulations have never been explored. The aim of the present study was to evaluate the antioxidant properties of vine-canes subcritical water extracts for use as active ingredients in the cosmetic industry. For that, the phenolic content and antioxidant activity of six vine-cane varieties, namely Alvarinho and Loureiro from the Minho region and Touriga Nacional and Tinta Roriz (TR) from both the Douro and Dão regions, were evaluated through spectrophotometric and chromatographic methods. All extracts presented similar antioxidant activity and the highest phenolic content was reported for TR variety from the Douro region (33.7 ± 1.9 mg GAE/g dw). The capacity of vine-cane extracts to capture reactive oxygen species superoxide (O<sub>2</sub><sup>∙−</sup>) was also studied, with the highest IC<sub>50</sub> value being obtained for Loureiro variety (56.68 ± 2.60 µg/mL). Furthermore, no adverse effects on HaCaT and HFF-1 dermal cell lines in concentrations below 100 and 1000 μg/mL, respectively, were determined. Finally, Loureiro vine-cane extract was incorporated into a topical formulation, and physical and microbiological properties were within expected values, demonstrating that vine-canes extracts can be successfully incorporated in cosmetic products.https://www.mdpi.com/1420-3049/25/13/2969vine-canessubcritical-water extractionantioxidantscytotoxicitycosmetic products |
| spellingShingle | Manuela M. Moreira Francisca Rodrigues Olena Dorosh Diana Pinto Paulo C. Costa Jaroslava Švarc-Gajić Cristina Delerue-Matos Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations Molecules vine-canes subcritical-water extraction antioxidants cytotoxicity cosmetic products |
| title | Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations |
| title_full | Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations |
| title_fullStr | Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations |
| title_full_unstemmed | Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations |
| title_short | Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations |
| title_sort | vine canes as a source of value added compounds for cosmetic formulations |
| topic | vine-canes subcritical-water extraction antioxidants cytotoxicity cosmetic products |
| url | https://www.mdpi.com/1420-3049/25/13/2969 |
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