Alveolar epithelial cells are competent producers of interstitial extracellular matrix with disease relevant plasticity in a human in vitro 3D model

Alveolar epithelial cells are competent producers of interstitial extracellular matrix with disease relevant plasticity in a human in vitro 3D model

Abstract Alveolar epithelial cells (AEC) have been implicated in pathological remodelling. We examined the capacity of AEC to produce extracellular matrix (ECM) and thereby directly contribute towards remodelling in chronic lung diseases. Cryopreserved type 2 AEC (AEC2) from healthy lungs and chroni...

Full description

Bibliographic Details
Main Authors: Oskar Rosmark, Måns Kadefors, Göran Dellgren, Christofer Karlsson, Anders Ericsson, Sandra Lindstedt, Johan Malmström, Oskar Hallgren, Anna-Karin Larsson-Callerfelt, Gunilla Westergren-Thorsson
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35011-z

Similar Items

Similar Items