Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension
The impact of antihypertensive therapy with the angiotensin-converting enzyme inhibitor enalapril (enap) and with enalapril in combination with the long-acting calcium channel blocker verapamil SR (isoptin SR) on changes of plasmatic, vascular-thrombocytic hemostasis and lipid peroxidation in patien...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2007-12-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/3319 |
| _version_ | 1797873258842816512 |
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| author | N. M. Krasnova E. A. Bushkova |
| author_facet | N. M. Krasnova E. A. Bushkova |
| author_sort | N. M. Krasnova |
| collection | DOAJ |
| description | The impact of antihypertensive therapy with the angiotensin-converting enzyme inhibitor enalapril (enap) and with enalapril in combination with the long-acting calcium channel blocker verapamil SR (isoptin SR) on changes of plasmatic, vascular-thrombocytic hemostasis and lipid peroxidation in patients with metabolic syndrome and arterial hypertension was studied. Combined therapy with enalapril and verapamil significantly reduces the fasting glucose and glycated hemoglobin concentrations, the aggregation activity of thrombocytes in the patient's blood, inhibits the lipid peroxidation, increases the level of high-density lipoprotein cholesterol, and decreases the coefficient of atherogenecity. Combined therapy with enalapril and verapamil SR can be recommended for treatment of arterial hypertension in patients with metabolic syndrome. |
| first_indexed | 2024-04-10T01:13:21Z |
| format | Article |
| id | doaj.art-b0024501111a4810a0359910087d0c17 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:13:21Z |
| publishDate | 2007-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-b0024501111a4810a0359910087d0c172023-03-13T09:58:07ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842007-12-0164586310.20538/1682-0363-2007-4-58-631975Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertensionN. M. Krasnova0E. A. Bushkova1Сибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскThe impact of antihypertensive therapy with the angiotensin-converting enzyme inhibitor enalapril (enap) and with enalapril in combination with the long-acting calcium channel blocker verapamil SR (isoptin SR) on changes of plasmatic, vascular-thrombocytic hemostasis and lipid peroxidation in patients with metabolic syndrome and arterial hypertension was studied. Combined therapy with enalapril and verapamil significantly reduces the fasting glucose and glycated hemoglobin concentrations, the aggregation activity of thrombocytes in the patient's blood, inhibits the lipid peroxidation, increases the level of high-density lipoprotein cholesterol, and decreases the coefficient of atherogenecity. Combined therapy with enalapril and verapamil SR can be recommended for treatment of arterial hypertension in patients with metabolic syndrome.https://bulletin.ssmu.ru/jour/article/view/3319метаболический синдромартериальная гипертензияагрегация тромбоцитовперекисное окисление липидовэналаприлверапамил ср |
| spellingShingle | N. M. Krasnova E. A. Bushkova Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension Бюллетень сибирской медицины метаболический синдром артериальная гипертензия агрегация тромбоцитов перекисное окисление липидов эналаприл верапамил ср |
| title | Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension |
| title_full | Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension |
| title_fullStr | Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension |
| title_full_unstemmed | Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension |
| title_short | Influence of combined antihypertensive therapy on plasmatic,vascular-thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension |
| title_sort | influence of combined antihypertensive therapy on plasmatic vascular thrombocytic hemostasis and lipid peroxidation in patientswith metabolic syndrome and arterial hypertension |
| topic | метаболический синдром артериальная гипертензия агрегация тромбоцитов перекисное окисление липидов эналаприл верапамил ср |
| url | https://bulletin.ssmu.ru/jour/article/view/3319 |
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