A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage

A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage

Stroke is a major reason for persistent disability due to insufficient treatment strategies beyond reperfusion, leading to oligodendrocyte death and axon demyelination, persistent inflammation and astrogliosis in peri-infarct areas. After injury, oligodendroglial precursor cells (OPCs) have been sho...

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Bibliographic Details
Main Authors: Luisa Werner, Michael Gliem, Nicole Rychlik, Goran Pavic, Laura Reiche, Frank Kirchhoff, Markley Silva Oliveira Junior, Joel Gruchot, Sven G. Meuth, Patrick Küry, Peter Göttle
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
ischemic stroke
neuroregeneration
myelin repair
oligodendrocyte
Online Access:https://www.mdpi.com/1422-0067/24/13/10972

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