Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer
Colorectal cancer (CRC) represents one of the most common malignancies worldwide. Research has indicated that functional gene changes such as single nucleotide polymorphism (SNP) influence carcinogenesis and metastasis and might have an influence on disease relapse. The aim of our study was to evalu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2017-05-01
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| Series: | Radiology and Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/raon-2016-0043 |
| _version_ | 1819116970525589504 |
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| author | Horvat Matej Potocnik Uros Repnik Katja Kavalar Rajko Zadnik Vesna Potrc Stojan Stabuc Borut |
| author_facet | Horvat Matej Potocnik Uros Repnik Katja Kavalar Rajko Zadnik Vesna Potrc Stojan Stabuc Borut |
| author_sort | Horvat Matej |
| collection | DOAJ |
| description | Colorectal cancer (CRC) represents one of the most common malignancies worldwide. Research has indicated that functional gene changes such as single nucleotide polymorphism (SNP) influence carcinogenesis and metastasis and might have an influence on disease relapse. The aim of our study was to evaluate the role of SNPs in selected genes as prognostic markers in resectable CRC. |
| first_indexed | 2024-12-22T05:25:33Z |
| format | Article |
| id | doaj.art-b009e3f22291426b9428294ab1e220f7 |
| institution | Directory Open Access Journal |
| issn | 1581-3207 |
| language | English |
| last_indexed | 2024-12-22T05:25:33Z |
| publishDate | 2017-05-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Radiology and Oncology |
| spelling | doaj.art-b009e3f22291426b9428294ab1e220f72022-12-21T18:37:36ZengSciendoRadiology and Oncology1581-32072017-05-0151215115910.1515/raon-2016-0043raon-2016-0043Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancerHorvat Matej0Potocnik Uros1Repnik Katja2Kavalar Rajko3Zadnik Vesna4Potrc Stojan5Stabuc Borut6Department of Oncology, University Medical Centre Maribor, Maribor, SloveniaCentre for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, SloveniaCentre for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, SloveniaDepartment of Pathology, University Medical Centre Maribor, Maribor, SloveniaEpidemiology and Cancer Registry, Institute of Oncology Ljubljana, Ljubljana, SloveniaDepartment of General and Abdominal Surgery, University Medical Centre Maribor, Maribor, SloveniaDepartment of Gastroenterology, University Medical Centre Ljubljana, Ljubljana, SloveniaColorectal cancer (CRC) represents one of the most common malignancies worldwide. Research has indicated that functional gene changes such as single nucleotide polymorphism (SNP) influence carcinogenesis and metastasis and might have an influence on disease relapse. The aim of our study was to evaluate the role of SNPs in selected genes as prognostic markers in resectable CRC.https://doi.org/10.1515/raon-2016-0043single nucleotide polymorphismcolorectal cancermacc1rad18mmp7sdf-1a |
| spellingShingle | Horvat Matej Potocnik Uros Repnik Katja Kavalar Rajko Zadnik Vesna Potrc Stojan Stabuc Borut Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer Radiology and Oncology single nucleotide polymorphism colorectal cancer macc1 rad18 mmp7 sdf-1a |
| title | Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer |
| title_full | Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer |
| title_fullStr | Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer |
| title_full_unstemmed | Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer |
| title_short | Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer |
| title_sort | single nucleotide polymorphisms in genes macc1 rad18 mmp7 and sdf 1a as prognostic factors in resectable colorectal cancer |
| topic | single nucleotide polymorphism colorectal cancer macc1 rad18 mmp7 sdf-1a |
| url | https://doi.org/10.1515/raon-2016-0043 |
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