Decreased uric acid levels in the acute phase of Plasmodium vivax malaria

Abstract INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS: We measured serum concentrations of uric acid in 60 symptomatic patients be...

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Main Authors: Luciano Teixeira Gomes, Ananda Karla Bellei, Denise Inácio de Andrade, Priscila Zanini Gotardo, Andreia Ferreira Nery, Cor Jesus Fernandes Fontes
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2019-05-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100649&lng=en&tlng=en
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author Luciano Teixeira Gomes
Ananda Karla Bellei
Denise Inácio de Andrade
Priscila Zanini Gotardo
Andreia Ferreira Nery
Cor Jesus Fernandes Fontes
author_facet Luciano Teixeira Gomes
Ananda Karla Bellei
Denise Inácio de Andrade
Priscila Zanini Gotardo
Andreia Ferreira Nery
Cor Jesus Fernandes Fontes
author_sort Luciano Teixeira Gomes
collection DOAJ
description Abstract INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS: We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax. RESULTS: Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001). CONCLUSIONS: Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase.
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spelling doaj.art-b011f75cc3b346d3afa980ac84f015cc2022-12-22T03:22:04ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492019-05-0152010.1590/0037-8682-0412-2017S0037-86822019000100649Decreased uric acid levels in the acute phase of Plasmodium vivax malariaLuciano Teixeira GomesAnanda Karla BelleiDenise Inácio de AndradePriscila Zanini GotardoAndreia Ferreira NeryCor Jesus Fernandes FontesAbstract INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS: We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax. RESULTS: Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001). CONCLUSIONS: Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100649&lng=en&tlng=enMalariaUric acidAcute phaseConvalescent phase
spellingShingle Luciano Teixeira Gomes
Ananda Karla Bellei
Denise Inácio de Andrade
Priscila Zanini Gotardo
Andreia Ferreira Nery
Cor Jesus Fernandes Fontes
Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
Revista da Sociedade Brasileira de Medicina Tropical
Malaria
Uric acid
Acute phase
Convalescent phase
title Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
title_full Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
title_fullStr Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
title_full_unstemmed Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
title_short Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
title_sort decreased uric acid levels in the acute phase of plasmodium vivax malaria
topic Malaria
Uric acid
Acute phase
Convalescent phase
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100649&lng=en&tlng=en
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