Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
Abstract INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS: We measured serum concentrations of uric acid in 60 symptomatic patients be...
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Format: | Article |
Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2019-05-01
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Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100649&lng=en&tlng=en |
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author | Luciano Teixeira Gomes Ananda Karla Bellei Denise Inácio de Andrade Priscila Zanini Gotardo Andreia Ferreira Nery Cor Jesus Fernandes Fontes |
author_facet | Luciano Teixeira Gomes Ananda Karla Bellei Denise Inácio de Andrade Priscila Zanini Gotardo Andreia Ferreira Nery Cor Jesus Fernandes Fontes |
author_sort | Luciano Teixeira Gomes |
collection | DOAJ |
description | Abstract INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS: We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax. RESULTS: Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001). CONCLUSIONS: Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase. |
first_indexed | 2024-04-12T18:03:32Z |
format | Article |
id | doaj.art-b011f75cc3b346d3afa980ac84f015cc |
institution | Directory Open Access Journal |
issn | 1678-9849 |
language | English |
last_indexed | 2024-04-12T18:03:32Z |
publishDate | 2019-05-01 |
publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
record_format | Article |
series | Revista da Sociedade Brasileira de Medicina Tropical |
spelling | doaj.art-b011f75cc3b346d3afa980ac84f015cc2022-12-22T03:22:04ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492019-05-0152010.1590/0037-8682-0412-2017S0037-86822019000100649Decreased uric acid levels in the acute phase of Plasmodium vivax malariaLuciano Teixeira GomesAnanda Karla BelleiDenise Inácio de AndradePriscila Zanini GotardoAndreia Ferreira NeryCor Jesus Fernandes FontesAbstract INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS: We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax. RESULTS: Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001). CONCLUSIONS: Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100649&lng=en&tlng=enMalariaUric acidAcute phaseConvalescent phase |
spellingShingle | Luciano Teixeira Gomes Ananda Karla Bellei Denise Inácio de Andrade Priscila Zanini Gotardo Andreia Ferreira Nery Cor Jesus Fernandes Fontes Decreased uric acid levels in the acute phase of Plasmodium vivax malaria Revista da Sociedade Brasileira de Medicina Tropical Malaria Uric acid Acute phase Convalescent phase |
title | Decreased uric acid levels in the acute phase of Plasmodium vivax malaria |
title_full | Decreased uric acid levels in the acute phase of Plasmodium vivax malaria |
title_fullStr | Decreased uric acid levels in the acute phase of Plasmodium vivax malaria |
title_full_unstemmed | Decreased uric acid levels in the acute phase of Plasmodium vivax malaria |
title_short | Decreased uric acid levels in the acute phase of Plasmodium vivax malaria |
title_sort | decreased uric acid levels in the acute phase of plasmodium vivax malaria |
topic | Malaria Uric acid Acute phase Convalescent phase |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100649&lng=en&tlng=en |
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