Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey
Abstract Despite having a high risk of soil-transmitted helminths (STHs) infection, no national level study has been conducted to assess incidence and correlates of STHs in Nepal. Thus, we hypothesized that micronutrients and social status are linked with incidence of STHs infection among 6–59 month...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-24634-3 |
| _version_ | 1828087210375643136 |
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| author | Suresh Mehata Kedar Raj Parajuli Binod Rayamajhee Uday Narayan Yadav Ranju Kumari Mehta Dipendra Raman Singh |
| author_facet | Suresh Mehata Kedar Raj Parajuli Binod Rayamajhee Uday Narayan Yadav Ranju Kumari Mehta Dipendra Raman Singh |
| author_sort | Suresh Mehata |
| collection | DOAJ |
| description | Abstract Despite having a high risk of soil-transmitted helminths (STHs) infection, no national level study has been conducted to assess incidence and correlates of STHs in Nepal. Thus, we hypothesized that micronutrients and social status are linked with incidence of STHs infection among 6–59 months children and 15–49 years non-pregnant women in Nepal and Kato-Katz technique was adopted to measure the type and intensity of STHs infections using fresh stool specimens and venous blood was used to examine micronutrients biomarkers. Anthropometric measurements such as height and weight, sociodemographic and health status were determined using structured questionnaire. Logistic regression was used to assess unadjusted and adjusted odds ratio (AOR) and the 95% CIs of ORs. The bivariate association of STHs was assessed with the covariates variables. Overall, 12% children and 19% non-pregnant women had STHs infection; A. lumbricoides was the predominant helminth in both study participants. In multivariate model; age, ethnicity, anaemia and zinc deficiency were associated with STHs infections in children. Similarly, higher odds of STHs occurrence was observed among non-pregnant women with vitamin A deficiency. Findings from this study suggest that high-risk population, with a focus on those of lower socioeconomic status should be on priority of deworming program, nutrition intervention, and mass administration of preventive chemotherapy and sanitation champions supplement to reduce the STHs infections in Nepal. |
| first_indexed | 2024-04-11T05:08:50Z |
| format | Article |
| id | doaj.art-b015198cf89d499faf1b14263c37ace0 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T05:08:50Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-b015198cf89d499faf1b14263c37ace02022-12-25T12:10:57ZengNature PortfolioScientific Reports2045-23222022-12-0112111310.1038/s41598-022-24634-3Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status surveySuresh Mehata0Kedar Raj Parajuli1Binod Rayamajhee2Uday Narayan Yadav3Ranju Kumari Mehta4Dipendra Raman Singh5Ministry of Health, Province 1Nutrition Section, Family Welfare Division, Department of Health ServicesSchool of Optometry and Vision Science, Faculty of Medicine and Health, UNSWNational Centre for Epidemiology and Population Health Research, School of Population Health, The Australian National UniversityLittle Buddha College of Health SciencesDepartment of Health ServicesAbstract Despite having a high risk of soil-transmitted helminths (STHs) infection, no national level study has been conducted to assess incidence and correlates of STHs in Nepal. Thus, we hypothesized that micronutrients and social status are linked with incidence of STHs infection among 6–59 months children and 15–49 years non-pregnant women in Nepal and Kato-Katz technique was adopted to measure the type and intensity of STHs infections using fresh stool specimens and venous blood was used to examine micronutrients biomarkers. Anthropometric measurements such as height and weight, sociodemographic and health status were determined using structured questionnaire. Logistic regression was used to assess unadjusted and adjusted odds ratio (AOR) and the 95% CIs of ORs. The bivariate association of STHs was assessed with the covariates variables. Overall, 12% children and 19% non-pregnant women had STHs infection; A. lumbricoides was the predominant helminth in both study participants. In multivariate model; age, ethnicity, anaemia and zinc deficiency were associated with STHs infections in children. Similarly, higher odds of STHs occurrence was observed among non-pregnant women with vitamin A deficiency. Findings from this study suggest that high-risk population, with a focus on those of lower socioeconomic status should be on priority of deworming program, nutrition intervention, and mass administration of preventive chemotherapy and sanitation champions supplement to reduce the STHs infections in Nepal.https://doi.org/10.1038/s41598-022-24634-3 |
| spellingShingle | Suresh Mehata Kedar Raj Parajuli Binod Rayamajhee Uday Narayan Yadav Ranju Kumari Mehta Dipendra Raman Singh Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey Scientific Reports |
| title | Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey |
| title_full | Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey |
| title_fullStr | Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey |
| title_full_unstemmed | Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey |
| title_short | Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey |
| title_sort | micronutrients deficiencies and its correlation with the soil transmitted helminthic infections among children and non pregnant women in nepal findings from nepal national micronutrient status survey |
| url | https://doi.org/10.1038/s41598-022-24634-3 |
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