Atypical presentation of mpox in Irrua environs: a case report
Abstract Background Mpox, previously known as monkeypox, -is an orthopoxvirus infection of the skin and previously a public health emergency of international concern. It reemerged in Nigeria over 5 years ago and has since spread to other parts of the world. This is a case report of a confirmed patie...
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | https://doi.org/10.1186/s13256-023-04225-0 |
| _version_ | 1827634200933564416 |
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| author | S. O. Oiwoh E. A. Tobin D. A. Asogun C. O. Erameh K. O. Iraoyah J. Okoeguale R. A. Eifediyi S. O. Samuel T. A. T. Salami S. A. Okogbenin |
| author_facet | S. O. Oiwoh E. A. Tobin D. A. Asogun C. O. Erameh K. O. Iraoyah J. Okoeguale R. A. Eifediyi S. O. Samuel T. A. T. Salami S. A. Okogbenin |
| author_sort | S. O. Oiwoh |
| collection | DOAJ |
| description | Abstract Background Mpox, previously known as monkeypox, -is an orthopoxvirus infection of the skin and previously a public health emergency of international concern. It reemerged in Nigeria over 5 years ago and has since spread to other parts of the world. This is a case report of a confirmed patient who was managed at Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria before the global surge. This report shows peculiar differences from previous patients managed at the same center in terms of the relatively prolonged eruptive phase, possible seasonal occurrence of mpox in the community, and some traditional care for mpox and skin rashes. It also corroborates previous reports of possible sexual transmission of mpox in Nigeria before the report from the global outbreak. Case presentation The patient is a 30-year-old Nigerian male artisan with a 2-month history of raised rashes on the body that started on the genitals then involved other parts of the body. There was history of sore throat and unprotected sex with a female partner with similar rash whose other sexual history could not be ascertained. There was also history of “seasonal” rash in his village for about 7 years prior to his symptoms. Examination showed multiple vesicles and some nodules (ulcerating, healing, and healed) on the face, trunk, limbs, gluteal region, scrotum, palms, and sole, an almost circumferential penile ulcer, and lymphadenopathy. Polymerase chain reaction skin samples sent for mpox returned positive, while retroviral and coronavirus disease 2019 screenings were negative. He was managed in isolation while contact tracing in the affected community was initiated. Conclusion Atypical presentations of mpox, as managed in Irrua before the global surge, emphasize the varied spectrum of presentations (typical and atypical) in Nigeria. Therefore, there is a need for a higher index of suspicion for the uncommon presentations which will strengthen case recognition, case management, and community-based interventions as well as surveillance in the prevention and control of mpox in Irrua, its environs, Nigeria, and the world. |
| first_indexed | 2024-03-09T15:10:05Z |
| format | Article |
| id | doaj.art-b018c0b613384480b9d2593e143f624b |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-03-09T15:10:05Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-b018c0b613384480b9d2593e143f624b2023-11-26T13:25:43ZengBMCJournal of Medical Case Reports1752-19472023-11-011711610.1186/s13256-023-04225-0Atypical presentation of mpox in Irrua environs: a case reportS. O. Oiwoh0E. A. Tobin1D. A. Asogun2C. O. Erameh3K. O. Iraoyah4J. Okoeguale5R. A. Eifediyi6S. O. Samuel7T. A. T. Salami8S. A. Okogbenin9Dermatology and Venereology Unit, Department of Internal Medicine, Irrua Specialist Teaching HospitalPan-African Network For Rapid Research, Response, Relief and Preparedness for Infectious Disease Epidemics (PANDORA-ID-NET), Institute of Viral Hemorrhagic Fevers and Emerging Pathogens (Formerly Institute of Lassa Fever Research and Control), Irrua Specialist Teaching HospitalPan-African Network For Rapid Research, Response, Relief and Preparedness for Infectious Disease Epidemics (PANDORA-ID-NET), Institute of Viral Hemorrhagic Fevers and Emerging Pathogens (Formerly Institute of Lassa Fever Research and Control), Irrua Specialist Teaching HospitalPan-African Network For Rapid Research, Response, Relief and Preparedness for Infectious Disease Epidemics (PANDORA-ID-NET), Institute of Viral Hemorrhagic Fevers and Emerging Pathogens (Formerly Institute of Lassa Fever Research and Control), Irrua Specialist Teaching HospitalInfectious Disease Unit, Department of Internal Medicine, Irrua Specialist Teaching HospitalPan-African Network For Rapid Research, Response, Relief and Preparedness for Infectious Disease Epidemics (PANDORA-ID-NET), Institute of Viral Hemorrhagic Fevers and Emerging Pathogens (Formerly Institute of Lassa Fever Research and Control), Irrua Specialist Teaching HospitalInstitute of Viral Hemorrhagic Fevers and Emerging Pathogens (formerly Institute of Lassa Fever Research and Control) and Department of Obstetrics and Gynecology, Irrua Specialist Teaching HospitalDepartment of Obstetrics and Gynecology, Irrua Specialist Teaching HospitalDermatology and Venereology Unit, Department of Internal Medicine, Irrua Specialist Teaching HospitalInstitute of Viral Hemorrhagic Fevers and Emerging Pathogens (formerly Institute of Lassa Fever Research and Control) and Department of Obstetrics and Gynecology, Irrua Specialist Teaching HospitalAbstract Background Mpox, previously known as monkeypox, -is an orthopoxvirus infection of the skin and previously a public health emergency of international concern. It reemerged in Nigeria over 5 years ago and has since spread to other parts of the world. This is a case report of a confirmed patient who was managed at Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria before the global surge. This report shows peculiar differences from previous patients managed at the same center in terms of the relatively prolonged eruptive phase, possible seasonal occurrence of mpox in the community, and some traditional care for mpox and skin rashes. It also corroborates previous reports of possible sexual transmission of mpox in Nigeria before the report from the global outbreak. Case presentation The patient is a 30-year-old Nigerian male artisan with a 2-month history of raised rashes on the body that started on the genitals then involved other parts of the body. There was history of sore throat and unprotected sex with a female partner with similar rash whose other sexual history could not be ascertained. There was also history of “seasonal” rash in his village for about 7 years prior to his symptoms. Examination showed multiple vesicles and some nodules (ulcerating, healing, and healed) on the face, trunk, limbs, gluteal region, scrotum, palms, and sole, an almost circumferential penile ulcer, and lymphadenopathy. Polymerase chain reaction skin samples sent for mpox returned positive, while retroviral and coronavirus disease 2019 screenings were negative. He was managed in isolation while contact tracing in the affected community was initiated. Conclusion Atypical presentations of mpox, as managed in Irrua before the global surge, emphasize the varied spectrum of presentations (typical and atypical) in Nigeria. Therefore, there is a need for a higher index of suspicion for the uncommon presentations which will strengthen case recognition, case management, and community-based interventions as well as surveillance in the prevention and control of mpox in Irrua, its environs, Nigeria, and the world.https://doi.org/10.1186/s13256-023-04225-0MpoxIrruaGenital presentationAtypical presentationsNodulopustular morphology |
| spellingShingle | S. O. Oiwoh E. A. Tobin D. A. Asogun C. O. Erameh K. O. Iraoyah J. Okoeguale R. A. Eifediyi S. O. Samuel T. A. T. Salami S. A. Okogbenin Atypical presentation of mpox in Irrua environs: a case report Journal of Medical Case Reports Mpox Irrua Genital presentation Atypical presentations Nodulopustular morphology |
| title | Atypical presentation of mpox in Irrua environs: a case report |
| title_full | Atypical presentation of mpox in Irrua environs: a case report |
| title_fullStr | Atypical presentation of mpox in Irrua environs: a case report |
| title_full_unstemmed | Atypical presentation of mpox in Irrua environs: a case report |
| title_short | Atypical presentation of mpox in Irrua environs: a case report |
| title_sort | atypical presentation of mpox in irrua environs a case report |
| topic | Mpox Irrua Genital presentation Atypical presentations Nodulopustular morphology |
| url | https://doi.org/10.1186/s13256-023-04225-0 |
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