SARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?

Introduction. During the current outbreak of Coronavirus disease 2019 (COVID-19), the way to manage patients with autoimmune diseases remains elusive due to limited data available. Case report. We presented a case of a COVID-19 positive 20-year-old female with prior history of Evans syndrome. The pa...

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Main Authors: Pantić Nikola, Mitrović Mirjana, Virijević Marijana, Sabljić Nikica, Pravdić Zlatko, Suvajdžić Nada
Format: Article
Language:English
Published: Military Health Department, Ministry of Defance, Serbia 2020-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2020/0042-84502000115P.pdf
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author Pantić Nikola
Mitrović Mirjana
Virijević Marijana
Sabljić Nikica
Pravdić Zlatko
Suvajdžić Nada
author_facet Pantić Nikola
Mitrović Mirjana
Virijević Marijana
Sabljić Nikica
Pravdić Zlatko
Suvajdžić Nada
author_sort Pantić Nikola
collection DOAJ
description Introduction. During the current outbreak of Coronavirus disease 2019 (COVID-19), the way to manage patients with autoimmune diseases remains elusive due to limited data available. Case report. We presented a case of a COVID-19 positive 20-year-old female with prior history of Evans syndrome. The patients remained asymptomatic even though she had been treated with immunosuppressants (prednisolone and azathioprine) together with romiplostim. Moreover, her course of infection was accompanied by thrombocytosis, although her platelet count was mostly be-low the reference range before the infection. The patient was monitored vigilantly, with special regard to platelet count and signs of thrombotic events. Conclusion. Platelet count monitoring and romiplostim administration should be performed more cautiously in chronic immune thrombocy-topenic patients infected by SARS-CoV-2.
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spelling doaj.art-b02207064b7d4a9ea01061e298e1257f2022-12-21T22:01:05ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202020-01-0177121348135010.2298/VSP200811115P0042-84502000115PSARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?Pantić Nikola0Mitrović Mirjana1Virijević Marijana2Sabljić Nikica3Pravdić Zlatko4Suvajdžić Nada5Clinical Center of Serbia, Clinic for Hematology, Belgrade, SerbiaClinical Center of Serbia, Clinic for Hematology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaClinical Center of Serbia, Clinic for Hematology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaClinical Center of Serbia, Clinic for Hematology, Belgrade, SerbiaClinical Center of Serbia, Clinic for Hematology, Belgrade, SerbiaClinical Center of Serbia, Clinic for Hematology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaIntroduction. During the current outbreak of Coronavirus disease 2019 (COVID-19), the way to manage patients with autoimmune diseases remains elusive due to limited data available. Case report. We presented a case of a COVID-19 positive 20-year-old female with prior history of Evans syndrome. The patients remained asymptomatic even though she had been treated with immunosuppressants (prednisolone and azathioprine) together with romiplostim. Moreover, her course of infection was accompanied by thrombocytosis, although her platelet count was mostly be-low the reference range before the infection. The patient was monitored vigilantly, with special regard to platelet count and signs of thrombotic events. Conclusion. Platelet count monitoring and romiplostim administration should be performed more cautiously in chronic immune thrombocy-topenic patients infected by SARS-CoV-2.http://www.doiserbia.nb.rs/img/doi/0042-8450/2020/0042-84502000115P.pdfcovid-19evans syndromepurpura, thrombocytopenic, idiopathicromiplostimthrombocytosis
spellingShingle Pantić Nikola
Mitrović Mirjana
Virijević Marijana
Sabljić Nikica
Pravdić Zlatko
Suvajdžić Nada
SARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?
Vojnosanitetski Pregled
covid-19
evans syndrome
purpura, thrombocytopenic, idiopathic
romiplostim
thrombocytosis
title SARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?
title_full SARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?
title_fullStr SARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?
title_full_unstemmed SARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?
title_short SARS-COV-2 infection in a patient with Evans syndrome: A silent enemy or an ally?
title_sort sars cov 2 infection in a patient with evans syndrome a silent enemy or an ally
topic covid-19
evans syndrome
purpura, thrombocytopenic, idiopathic
romiplostim
thrombocytosis
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2020/0042-84502000115P.pdf
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