Interferon Inhibition Enhances the Pilot-Scale Production of Rabies Virus in Human Diploid MRC-5 Cells

Interferon Inhibition Enhances the Pilot-Scale Production of Rabies Virus in Human Diploid MRC-5 Cells

Inactivated vaccines based on cell culture are very useful in the prevention and control of many diseases. The most popular strategy for the production of inactivated vaccines is based on monkey-derived Vero cells, which results in high productivity of the virus but has a certain carcinogenic risk d...

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Bibliographic Details
Main Authors:	Xiao Yang, Mingming Wan, Linjun Cai, Ali Hou, Bo Sun, Yan Zhou, Feng Gao, Weiheng Su, Chunlai Jiang
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	Viruses
Subjects:	inactivated vaccine MRC-5 cell IFN response IFNAR1-deficient cell line pilot scale production rabies virus
Online Access:	https://www.mdpi.com/1999-4915/14/1/49

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