Recent Advances in Potential Health Benefits of Quercetin
Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively studied. Its strong antioxidant properties enable it...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/16/7/1020 |
| _version_ | 1797587886718058496 |
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| author | Fatemeh Aghababaei Milad Hadidi |
| author_facet | Fatemeh Aghababaei Milad Hadidi |
| author_sort | Fatemeh Aghababaei |
| collection | DOAJ |
| description | Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively studied. Its strong antioxidant properties enable it to scavenge free radicals, reduce oxidative stress, and protect against cellular damage. Quercetin’s anti-inflammatory properties involve inhibiting the production of inflammatory cytokines and enzymes, making it a potential therapeutic agent for various inflammatory conditions. It also exhibits anticancer effects by inhibiting cancer cell proliferation and inducing apoptosis. Finally, quercetin has cardiovascular benefits such as lowering blood pressure, reducing cholesterol levels, and improving endothelial function, making it a promising candidate for preventing and treating cardiovascular diseases. This review provides an overview of the chemical structure, biological activities, and bioavailability of quercetin, as well as the different delivery systems available for quercetin. Incorporating quercetin-rich foods into the diet or taking quercetin supplements may be beneficial for maintaining good health and preventing chronic diseases. As research progresses, the future perspectives of quercetin appear promising, with potential applications in nutraceuticals, pharmaceuticals, and functional foods to promote overall well-being and disease prevention. However, further studies are needed to elucidate its mechanisms of action, optimize its bioavailability, and assess its long-term safety for widespread utilization. |
| first_indexed | 2024-03-11T00:45:10Z |
| format | Article |
| id | doaj.art-b0255f953a354cff9320e0d18a5705a9 |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-11T00:45:10Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-b0255f953a354cff9320e0d18a5705a92023-11-18T20:53:15ZengMDPI AGPharmaceuticals1424-82472023-07-01167102010.3390/ph16071020Recent Advances in Potential Health Benefits of QuercetinFatemeh Aghababaei0Milad Hadidi1Centre d’Innovació, Recerca i Transferència en Tecnologia dels Aliments (CIRTTA), TECNIO-UAB, XIA, Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, UAB-Campus, 08193 Bellaterra, SpainDepartment of Organic Chemistry, Faculty of Chemical Sciences and Technologies, University of Castilla-La Mancha, 13071 Ciudad Real, SpainQuercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively studied. Its strong antioxidant properties enable it to scavenge free radicals, reduce oxidative stress, and protect against cellular damage. Quercetin’s anti-inflammatory properties involve inhibiting the production of inflammatory cytokines and enzymes, making it a potential therapeutic agent for various inflammatory conditions. It also exhibits anticancer effects by inhibiting cancer cell proliferation and inducing apoptosis. Finally, quercetin has cardiovascular benefits such as lowering blood pressure, reducing cholesterol levels, and improving endothelial function, making it a promising candidate for preventing and treating cardiovascular diseases. This review provides an overview of the chemical structure, biological activities, and bioavailability of quercetin, as well as the different delivery systems available for quercetin. Incorporating quercetin-rich foods into the diet or taking quercetin supplements may be beneficial for maintaining good health and preventing chronic diseases. As research progresses, the future perspectives of quercetin appear promising, with potential applications in nutraceuticals, pharmaceuticals, and functional foods to promote overall well-being and disease prevention. However, further studies are needed to elucidate its mechanisms of action, optimize its bioavailability, and assess its long-term safety for widespread utilization.https://www.mdpi.com/1424-8247/16/7/1020antioxidative activityfree radicalsanticancer activityanti-inflammatorychronic diseasespharmaceutical applications |
| spellingShingle | Fatemeh Aghababaei Milad Hadidi Recent Advances in Potential Health Benefits of Quercetin Pharmaceuticals antioxidative activity free radicals anticancer activity anti-inflammatory chronic diseases pharmaceutical applications |
| title | Recent Advances in Potential Health Benefits of Quercetin |
| title_full | Recent Advances in Potential Health Benefits of Quercetin |
| title_fullStr | Recent Advances in Potential Health Benefits of Quercetin |
| title_full_unstemmed | Recent Advances in Potential Health Benefits of Quercetin |
| title_short | Recent Advances in Potential Health Benefits of Quercetin |
| title_sort | recent advances in potential health benefits of quercetin |
| topic | antioxidative activity free radicals anticancer activity anti-inflammatory chronic diseases pharmaceutical applications |
| url | https://www.mdpi.com/1424-8247/16/7/1020 |
| work_keys_str_mv | AT fatemehaghababaei recentadvancesinpotentialhealthbenefitsofquercetin AT miladhadidi recentadvancesinpotentialhealthbenefitsofquercetin |