CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASES

Objective To investigate the clinical features of neonates with enterovirus encephalitis, and to prevent the outbreak of enterovirus infection by improving the early identification of this disease. Methods A total of 12 neonates with enterovirus encephalitis who were admitted to our hospital from Ju...

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Main Author: XI Hongmin, SHAO Hui, GAO Fang, JIANG Hong, LI Xianghong
Format: Article
Language:zho
Published: Editorial Office of Journal of Precision Medicine 2023-02-01
Series:精准医学杂志
Subjects:
Online Access:https://jpmed.qdu.edu.cn/fileup/2096-529X/PDF/202301006.pdf
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author XI Hongmin, SHAO Hui, GAO Fang, JIANG Hong, LI Xianghong
author_facet XI Hongmin, SHAO Hui, GAO Fang, JIANG Hong, LI Xianghong
author_sort XI Hongmin, SHAO Hui, GAO Fang, JIANG Hong, LI Xianghong
collection DOAJ
description Objective To investigate the clinical features of neonates with enterovirus encephalitis, and to prevent the outbreak of enterovirus infection by improving the early identification of this disease. Methods A total of 12 neonates with enterovirus encephalitis who were admitted to our hospital from June 2019 to June 2022 were enrolled and analyzed in terms of clinical features and laboratory examination. The key points of treatment were summarized, and their prognosis was assessed. ResultsAmong the 12 neonates, 7 were preterm infants, with the clinical manifestations of nonspecific sepsis-like symptoms and normal or mildly elevated inflammatory markers. All neonates tested positive for enterovirus nucleic acid in cerebrospinal fluid. All neonates were given standard isolation, intravenous injection of human immunoglobulin, and symptomatic supportive treatment and achieved a good prognosis after treatment. Conclusion Neonates with enterovirus encephalitis often have atypical clinical manifestations and thus require early identification and targeted strategies for the prevention and control of infection.
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spelling doaj.art-b026f424b72744ea84919edf49460c2b2024-03-12T06:46:56ZzhoEditorial Office of Journal of Precision Medicine精准医学杂志2096-529X2023-02-01381222410.13362/j.jpmed.202301006CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASESXI Hongmin, SHAO Hui, GAO Fang, JIANG Hong, LI Xianghong0Department of Neonatology, The Affiliated Hospital of Qingdao University, Qingdao 266555, ChinaObjective To investigate the clinical features of neonates with enterovirus encephalitis, and to prevent the outbreak of enterovirus infection by improving the early identification of this disease. Methods A total of 12 neonates with enterovirus encephalitis who were admitted to our hospital from June 2019 to June 2022 were enrolled and analyzed in terms of clinical features and laboratory examination. The key points of treatment were summarized, and their prognosis was assessed. ResultsAmong the 12 neonates, 7 were preterm infants, with the clinical manifestations of nonspecific sepsis-like symptoms and normal or mildly elevated inflammatory markers. All neonates tested positive for enterovirus nucleic acid in cerebrospinal fluid. All neonates were given standard isolation, intravenous injection of human immunoglobulin, and symptomatic supportive treatment and achieved a good prognosis after treatment. Conclusion Neonates with enterovirus encephalitis often have atypical clinical manifestations and thus require early identification and targeted strategies for the prevention and control of infection.https://jpmed.qdu.edu.cn/fileup/2096-529X/PDF/202301006.pdfenterovirus infections|encephalitis, viral|infant, newborn|signs and symptoms|therapeutics
spellingShingle XI Hongmin, SHAO Hui, GAO Fang, JIANG Hong, LI Xianghong
CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASES
精准医学杂志
enterovirus infections|encephalitis, viral|infant, newborn|signs and symptoms|therapeutics
title CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASES
title_full CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASES
title_fullStr CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASES
title_full_unstemmed CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASES
title_short CLINICAL FEATURES AND OUTCOME OF NEONATES WITH ENTEROVIRUS ENCEPHALITIS: AN ANALYSIS OF 12 CASES
title_sort clinical features and outcome of neonates with enterovirus encephalitis an analysis of 12 cases
topic enterovirus infections|encephalitis, viral|infant, newborn|signs and symptoms|therapeutics
url https://jpmed.qdu.edu.cn/fileup/2096-529X/PDF/202301006.pdf
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