Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease
Inflammatory pseudotumor (IPT) is a rare disease that is often misinterpreted as a lymphoma or carcinoma. It may involve different body regions but most commonly the lungs and the orbital cavity. We report the case of a patient affected by an IPT of the trigeminal and facial nerves. A 69-year-old ma...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2020-01-01
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| Series: | The Surgery Journal |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1702921 |
| _version_ | 1818646368549339136 |
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| author | Giacomo Fiacchini Christina Cambi Antonio Gaetano Tavoni Luca Bruschini Roberto Castellana Iacopo Dallan Stefano Berrettini |
| author_facet | Giacomo Fiacchini Christina Cambi Antonio Gaetano Tavoni Luca Bruschini Roberto Castellana Iacopo Dallan Stefano Berrettini |
| author_sort | Giacomo Fiacchini |
| collection | DOAJ |
| description | Inflammatory pseudotumor (IPT) is a rare disease that is often misinterpreted as a lymphoma or carcinoma. It may involve different body regions but most commonly the lungs and the orbital cavity. We report the case of a patient affected by an IPT of the trigeminal and facial nerves. A 69-year-old male presented to our hospital with a right facial palsy arisen suddenly 2 days before. A magnetic resonance imaging (MRI) of the head showed an abnormal mass with homogeneous enhancement involving the deep lobe of the parotid gland, the parapharyngeal space, and the infratemporal fossa, extending along the trigeminal nerve and the facial nerve. The patient was planned for multiple transnasal biopsies in the nasopharynx, the region of the foramen ovale, and the deep lobe of the parotid gland, but the results were inconclusive, with no evidence of a malignant process. We considered the possibility that the lesion could be an IPT, and the patient was treated with prednisone and cyclophosphamide. Three months after the conclusion of the treatment, an MRI showed a complete radiological response. |
| first_indexed | 2024-12-17T00:45:32Z |
| format | Article |
| id | doaj.art-b028783d2f544b00b3016a1b846ca07e |
| institution | Directory Open Access Journal |
| issn | 2378-5128 2378-5136 |
| language | English |
| last_indexed | 2024-12-17T00:45:32Z |
| publishDate | 2020-01-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | The Surgery Journal |
| spelling | doaj.art-b028783d2f544b00b3016a1b846ca07e2022-12-21T22:09:55ZengThieme Medical Publishers, Inc.The Surgery Journal2378-51282378-51362020-01-010601e33e3610.1055/s-0040-1702921Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare DiseaseGiacomo Fiacchini0Christina Cambi1Antonio Gaetano Tavoni2Luca Bruschini3Roberto Castellana4Iacopo Dallan5Stefano Berrettini6Otolaryngology, Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, ItalyOtolaryngology, Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, ItalyClinical Immunology Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, ItalyOtolaryngology, Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, ItalyRadiology Department, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, ItalyOtolaryngology, Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, ItalyOtolaryngology, Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, ItalyInflammatory pseudotumor (IPT) is a rare disease that is often misinterpreted as a lymphoma or carcinoma. It may involve different body regions but most commonly the lungs and the orbital cavity. We report the case of a patient affected by an IPT of the trigeminal and facial nerves. A 69-year-old male presented to our hospital with a right facial palsy arisen suddenly 2 days before. A magnetic resonance imaging (MRI) of the head showed an abnormal mass with homogeneous enhancement involving the deep lobe of the parotid gland, the parapharyngeal space, and the infratemporal fossa, extending along the trigeminal nerve and the facial nerve. The patient was planned for multiple transnasal biopsies in the nasopharynx, the region of the foramen ovale, and the deep lobe of the parotid gland, but the results were inconclusive, with no evidence of a malignant process. We considered the possibility that the lesion could be an IPT, and the patient was treated with prednisone and cyclophosphamide. Three months after the conclusion of the treatment, an MRI showed a complete radiological response.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1702921facial nerveinflammatory pseudotumorskull basetrigeminal nerve |
| spellingShingle | Giacomo Fiacchini Christina Cambi Antonio Gaetano Tavoni Luca Bruschini Roberto Castellana Iacopo Dallan Stefano Berrettini Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease The Surgery Journal facial nerve inflammatory pseudotumor skull base trigeminal nerve |
| title | Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease |
| title_full | Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease |
| title_fullStr | Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease |
| title_full_unstemmed | Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease |
| title_short | Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease |
| title_sort | skull base inflammatory pseudotumor involving the trigeminal and facial nerves a singular presentation of a rare disease |
| topic | facial nerve inflammatory pseudotumor skull base trigeminal nerve |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1702921 |
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