Alteration of Biomolecular Conformation by Aluminum-Implications for Protein Misfolding Disease

Alteration of Biomolecular Conformation by Aluminum-Implications for Protein Misfolding Disease

The natural element aluminum possesses a number of unique biochemical and biophysical properties that make this highly neurotoxic species deleterious towards the structural integrity, conformation, reactivity and stability of several important biomolecules. These include aluminum’s <b>(i)</...

Full description

Bibliographic Details
Main Authors:	Yuhai Zhao, Aileen I. Pogue, Peter N. Alexandrov, Leslie G. Butler, Wenhong Li, Vivian R. Jaber, Walter J. Lukiw
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Molecules
Subjects:	aluminum Alzheimer’s disease (AD) biomolecules adenosine triphosphate (ATP) histone linker proteins (H1 class) prion disease (PrD)
Online Access:	https://www.mdpi.com/1420-3049/27/16/5123

Similar Items

Recent Advances in Our Molecular and Mechanistic Understanding of Misfolded Cellular Proteins in Alzheimer’s Disease (AD) and Prion Disease (PrD)
by: Walter J. Lukiw
Published: (2022-01-01)

SARS-CoV-2, long COVID, prion disease and neurodegeneration
by: Yuhai Zhao, et al.
Published: (2022-09-01)

Application of α-Syn Real-Time Quaking-Induced Conversion for Brain and Skin Specimens of the Chinese Patients With Parkinson’s Disease
by: Dong-Dong Chen, et al.
Published: (2022-07-01)

Intracellular ATP Concentration and Implication for Cellular Evolution
by: Jack V. Greiner, et al.
Published: (2021-11-01)

Adenosine-5'-triphosphate (ATP) supplementation improves low peak muscle torque and torque fatigue during repeated high intensity exercise sets
by: Rathmacher John A, et al.
Published: (2012-10-01)

Telmisartan Protects Mitochondrial Function, Gait, and Neuronal Apoptosis by Activating the Akt/GSK3β/PGC1α Pathway in an MPTP-Induced Mouse Model of Parkinson's Disease
by: Bipul Ray, et al.
Published: (2024-02-01)

ATP MONITORING AS AN EXPRESS METHOD TO DETERMINE OBJECT CONTAMINATION
by: T. Volovyk, et al.
Published: (2019-12-01)

microRNA-146a Signaling in Alzheimer's Disease (AD) and Prion Disease (PrD)
by: Walter J. Lukiw, et al.
Published: (2020-06-01)

CD39 abrogates platelet-derived factors induced IL-1β expression in the human placenta
by: Désirée Forstner, et al.
Published: (2023-05-01)

Mechanosensitive Hydrolysis of ATP and ADP in Lamina Propria of the Murine Bladder by Membrane-Bound and Soluble Nucleotidases
by: Mafalda S. L. Aresta Branco, et al.
Published: (2022-06-01)

Utility of the Teslar Facial Massager for Skin Elasticity and the Mechanism of its Effects
by: Kazuhisa Maeda, et al.
Published: (2018-08-01)

Examining Skin Recovery After a 3% Aqueous Hydrogen Peroxide (H2O2) Treatment Using ATP Biofluorescence
by: Gruber JV, et al.
Published: (2022-05-01)

Evaluation of bioenergetic and mitochondrial function in liver transplantation
by: Rui Miguel Martins, et al.
Published: (2019-03-01)

FERROPTOSIS AND ITS POTENTIAL ROLE IN CARDIOVASCULAR DISEASES
by: Yavor Kashlov, et al.
Published: (2019-03-01)

Adenosine thiamine triphosphate and adenosine thiamine triphosphate hydrolase activity in animal tissues
by: A. F. Makarchikov, et al.
Published: (2018-07-01)

Prion-like Domains in Spike Protein of SARS-CoV-2 Differ across Its Variants and Enable Changes in Affinity to ACE2
by: George Tetz, et al.
Published: (2022-01-01)

Innovations in biomolecular modeling and simulations /
by: Schlick, Tamar 433846, et al.
Published: (c201)

Lysing Agents for Characteristic Polluting Microorganisms in Jet Fuels
by: Yun Xiong, et al.
Published: (2019-06-01)

Diagnosis in Scrapie: Conventional Methods and New Biomarkers
by: Diego Sola, et al.
Published: (2023-11-01)

Molecular Dynamics Simulations Capture the Misfolding of the Bovine Prion Protein at Acidic pH
by: Chin Jung Cheng, et al.
Published: (2014-02-01)

Cinnamaldehyde has ameliorative effects on rabbit spinal cord ischemia and reperfusion injury
by: Pınar Kuru Bektaşoğlu, et al.
Published: (2024-01-01)

ATP Consumption Is Coupled with Endocytosis in Exudated Neutrophils
by: Duo Wang, et al.
Published: (2023-05-01)

Recent Advances in Design Strategies and Imaging Applications of Fluorescent Probes for ATP
by: Qing-Song Gu, et al.
Published: (2023-07-01)

Prebiotic Synthesis of ATP: A Terrestrial Volcanism-Dependent Pathway
by: Xin-Yi Chu, et al.
Published: (2023-03-01)

Correlating nanoscale motion and ATP production in healthy and favism erythrocytes: a real-time nanomotion sensor study
by: Marco Girasole, et al.
Published: (2023-06-01)

Nicotinamide metabolism modulates the proliferation/differentiation balance and senescence of human primary keratinocytes
by: Tan, Chye Ling, et al.
Published: (2019)

Corrigendum: ATPase Inhibitory Factor 1 Is Critical for Regulating Sevoflurane-Induced Microglial Inflammatory Responses and Caspase-3 Activation
by: Yaru Xu, et al.
Published: (2022-05-01)

ATPase Inhibitory Factor 1 Is Critical for Regulating Sevoflurane-Induced Microglial Inflammatory Responses and Caspase-3 Activation
by: Yaru Xu, et al.
Published: (2021-12-01)

ENERGI-F703 gel, as a new topical treatment for diabetic foot and leg ulcers: A multicenter, randomized, double-blind, phase II trial
by: Jui-Yung Yang, et al.
Published: (2022-09-01)

Locally-Induced CaMKII Translocation Requires Nucleotide Binding
by: Zachary T. Fitzgerald, et al.
Published: (2020-02-01)

Editorial: P2X7 Receptor Function in Neurodegenerative Diseases
by: Robson Xavier Faria, et al.
Published: (2021-11-01)

microRNA-146a as a biomarker for transmissible spongiform encephalopathy
by: Aileen Pogue, et al.
Published: (2022-03-01)

Biomolecular Structures /
by: Gamboa, Amari, author 648826
Published: (2012)

A comparison of adenosine triphosphate with other metrics of microbial biomass in a gradient from the North Atlantic to the Chesapeake Bay
by: Alexander B. Bochdansky, et al.
Published: (2024-01-01)

Can the adenosine triphosphate (ATP) bioluminescence assay be used as an indicator for hospital cleaning? – A pilot study
by: Niephaus, Valerie, et al.
Published: (2024-02-01)

Optimization of Aptamer-Based Electrochemical Biosensor for ATP Detection Using Screen-Printed Carbon Electrode/Gold Nanoparticles (SPCE/AuNP)
by: Rahmaniar Mulyani, et al.
Published: (2022-09-01)

Erratum: Follow Your Nose: A Key Clue to Understanding and Treating COVID-19
by: Frontiers Production Office
Published: (2021-12-01)

Monitoring of endoscope reprocessing with an adenosine triphosphate (ATP) bioluminescence method
by: Parohl, Nina, et al.
Published: (2017-03-01)

Follow Your Nose: A Key Clue to Understanding and Treating COVID-19
by: Christopher Edwards, et al.
Published: (2021-11-01)

Prion infectivity is encoded exclusively within the structure of proteinase K-resistant fragments of synthetically generated recombinant PrPSc
by: Fei Wang, et al.
Published: (2018-04-01)