Consistent Inverse Associations of Total, “Bioavailable”, Free, and “Non-Bioavailable” Vitamin D with Incidence of Diabetes among Older Adults with Lower Baseline HbA<sub>1c</sub> (≤6%) Levels

Consistent Inverse Associations of Total, “Bioavailable”, Free, and “Non-Bioavailable” Vitamin D with Incidence of Diabetes among Older Adults with Lower Baseline HbA<sub>1c</sub> (≤6%) Levels

Background: Serum 25-hydroxyvitamin (25(OH)D) levels are inversely associated with risk of diabetes. The “free hormone hypothesis” suggests potential effects to be mainly related to concentrations of “bioavailable” and free rather than total 25(OH)D. We assessed associations of serum concentrations...

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Bibliographic Details
Main Authors: Anna Zhu, Sabine Kuznia, Tobias Niedermaier, Bernd Holleczek, Ben Schöttker, Hermann Brenner
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Nutrients
Subjects:
vitamin D
vitamin D-binding protein
bioavailable 25(OH)D
free 25(OH)D
type 2 diabetes
Online Access:https://www.mdpi.com/2072-6643/14/16/3282

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