Does the time to diagnosis and treatment influence outcome in adults with pleural infections
ABSTRACTObjective To investigate the effect of early diagnosis and intervention in adult patients with complicated parapneumonic pleural effusion or pleural empyema and the impact on outcomes.Methods A systematic review based on a literature search of the PubMed database was performed.Results Eleven...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-01-01
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| Series: | European Clinical Respiratory Journal |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20018525.2023.2174645 |
| _version_ | 1827631224308367360 |
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| author | Mads Brögger Klausen Christian Laursen Morten Bendixen Babu Naidu Eihab O Bedawi Najib. M. Rahman Thomas Decker Christensen |
| author_facet | Mads Brögger Klausen Christian Laursen Morten Bendixen Babu Naidu Eihab O Bedawi Najib. M. Rahman Thomas Decker Christensen |
| author_sort | Mads Brögger Klausen |
| collection | DOAJ |
| description | ABSTRACTObjective To investigate the effect of early diagnosis and intervention in adult patients with complicated parapneumonic pleural effusion or pleural empyema and the impact on outcomes.Methods A systematic review based on a literature search of the PubMed database was performed.Results Eleven eligible studies were included; nine observational studies and two randomised controlled trials totalling a study population of 10,717 patients. The studies were conducted from 1992 to 2018, all in Europe and Northern America except one. Results varied between studies, but a trend towards better outcome in patients with shorter duration of symptoms and quicker initiation of treatment was found. We found that duration of symptoms before treatment may affect length of hospital stay, rate of conversion to open surgery, and frequency of complications.Conclusion We found that an earlier intervention in adults suffering from complicated parapneumonic pleural effusion and pleural empyema may potentially improve the outcome of patients in terms of length of stay, conversion to open surgery, and general complications following treatment, but not regarding mortality. Further studies are required to specify the timing of each intervention, and direct comparison in early management of interventions. |
| first_indexed | 2024-03-09T14:17:58Z |
| format | Article |
| id | doaj.art-b02b0feb9366489cbe0a48c1e66f8909 |
| institution | Directory Open Access Journal |
| issn | 2001-8525 |
| language | English |
| last_indexed | 2024-03-09T14:17:58Z |
| publishDate | 2023-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | European Clinical Respiratory Journal |
| spelling | doaj.art-b02b0feb9366489cbe0a48c1e66f89092023-11-28T19:19:58ZengTaylor & Francis GroupEuropean Clinical Respiratory Journal2001-85252023-01-0110110.1080/20018525.2023.2174645Does the time to diagnosis and treatment influence outcome in adults with pleural infectionsMads Brögger Klausen0Christian Laursen1Morten Bendixen2Babu Naidu3Eihab O Bedawi4Najib. M. Rahman5Thomas Decker Christensen6Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, DenmarkDepartment of Respiratory Medicine, Odense University Hospital, Odense, DenmarkDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, DenmarkDepartment of Thoracic Surgery, Queen Elizabeth Hospital Birmingham, UK & Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UKNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UKNIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UKDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, DenmarkABSTRACTObjective To investigate the effect of early diagnosis and intervention in adult patients with complicated parapneumonic pleural effusion or pleural empyema and the impact on outcomes.Methods A systematic review based on a literature search of the PubMed database was performed.Results Eleven eligible studies were included; nine observational studies and two randomised controlled trials totalling a study population of 10,717 patients. The studies were conducted from 1992 to 2018, all in Europe and Northern America except one. Results varied between studies, but a trend towards better outcome in patients with shorter duration of symptoms and quicker initiation of treatment was found. We found that duration of symptoms before treatment may affect length of hospital stay, rate of conversion to open surgery, and frequency of complications.Conclusion We found that an earlier intervention in adults suffering from complicated parapneumonic pleural effusion and pleural empyema may potentially improve the outcome of patients in terms of length of stay, conversion to open surgery, and general complications following treatment, but not regarding mortality. Further studies are required to specify the timing of each intervention, and direct comparison in early management of interventions.https://www.tandfonline.com/doi/10.1080/20018525.2023.2174645Pleural empyemadiagnosistreatmentadult |
| spellingShingle | Mads Brögger Klausen Christian Laursen Morten Bendixen Babu Naidu Eihab O Bedawi Najib. M. Rahman Thomas Decker Christensen Does the time to diagnosis and treatment influence outcome in adults with pleural infections European Clinical Respiratory Journal Pleural empyema diagnosis treatment adult |
| title | Does the time to diagnosis and treatment influence outcome in adults with pleural infections |
| title_full | Does the time to diagnosis and treatment influence outcome in adults with pleural infections |
| title_fullStr | Does the time to diagnosis and treatment influence outcome in adults with pleural infections |
| title_full_unstemmed | Does the time to diagnosis and treatment influence outcome in adults with pleural infections |
| title_short | Does the time to diagnosis and treatment influence outcome in adults with pleural infections |
| title_sort | does the time to diagnosis and treatment influence outcome in adults with pleural infections |
| topic | Pleural empyema diagnosis treatment adult |
| url | https://www.tandfonline.com/doi/10.1080/20018525.2023.2174645 |
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