Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity
Many biopharmaceuticals exhibit mixed heterogeneity in their post-translational modifications (PTMs) that are essential for their function. Here the authors use a combination of mass spectrometry techniques to analyse human erythropoietin (EPO) and properdin to discover new PTMs on properdin and der...
প্রধান লেখক: | , , , , , |
---|---|
বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Nature Portfolio
2016-11-01
|
মালা: | Nature Communications |
অনলাইন ব্যবহার করুন: | https://doi.org/10.1038/ncomms13397 |