Integrated transcriptomic and metabolomic analysis reveals the metabolic programming of GM-CSF- and M-CSF- differentiated mouse macrophages

Integrated transcriptomic and metabolomic analysis reveals the metabolic programming of GM-CSF- and M-CSF- differentiated mouse macrophages

Macrophages play a critical role in the inflammatory response and tumor development. Macrophages are primarily divided into pro-inflammatory M1-like and anti-inflammatory M2-like macrophages based on their activation status and functions. In vitro macrophage models could be derived from mouse bone m...

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Bibliographic Details
Main Authors: Qianyue Zhang, Qiaoling Song, Shan Liu, Yuting Xu, Danling Gao, Peizhe Lu, Yuantao Liu, Guanghui Zhao, Lihong Wu, Chenyang Zhao, Jinbo Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
macrophage differentiation
GM-CSF
M-CSF
immunometabolism
transcriptome
metabolome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1230772/full

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