Assessment of echinococcosis control in Tibet Autonomous Region, China
Abstract Background In China the highest prevalence of echinococcosis is in Tibet Autonomous Region (TAR). The government has issued documents and implemented comprehensive prevention and control measures focusing on controlling the source of infection of echinococcosis. It was very important to und...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | Infectious Diseases of Poverty |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40249-022-00987-9 |
| _version_ | 1828228217054429184 |
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| author | Liying Wang Quzhen Gongsang Huasheng Pang Min Qin Ying Wang Jingzhong Li Roger Frutos Laurent Gavotte |
| author_facet | Liying Wang Quzhen Gongsang Huasheng Pang Min Qin Ying Wang Jingzhong Li Roger Frutos Laurent Gavotte |
| author_sort | Liying Wang |
| collection | DOAJ |
| description | Abstract Background In China the highest prevalence of echinococcosis is in Tibet Autonomous Region (TAR). The government has issued documents and implemented comprehensive prevention and control measures focusing on controlling the source of infection of echinococcosis. It was very important to understand the implementation and effect of infectious source control measures. The purpose of this study was to examine the implementation of measures to control infectious source (domestic and stray dogs) in TAR and to assess their effectiveness. Methods We collected data on domestic dog registration and deworming and stray dog sheltering in 74 counties/districts in the TAR from 2017 to 2019. Fecal samples from domestic dogs were collected from randomly selected towns to determine Echinococcus infection in dogs using coproantigen ELISA. We analyzed the data to compare the canine rate of infection between 2016 and 2019. The data analysis was performed by SPSS statistical to compare dog infection rate in 2016 and 2019 by chi-square test, and ArcGIS was used for mapping. Results From 2017 to 2019, 84 stray dog shelters were built in TAR, and accumulatively 446,660 stray or infected dogs were arrested, sheltered, or disposed of. The number of domestic dogs went downward, with an increased registration management rate of 78.4% (2017), 88.8% (2018), and 99.0% (2019). Dogs were dewormed 5 times in 2017, 12 times in 2018, and 12 times in 2019. The dog infection rate was 1.7% (252/14,584) in 2019, significantly lower than 7.3% (552/7564) from the survey of echinococcosis prevalence in Tibet in 2016 (P < 0.05). Conclusion Between 2017 and 2019, the number of stray dogs and infection rate of Echinococcus spp. in domestic dogs decreased significantly, indicating that dogs were effectively controlled as a source of infection in TAR and reflecting a significant decrease in the risk of echinococcosis transmission. Graphical Abstract |
| first_indexed | 2024-04-12T18:18:11Z |
| format | Article |
| id | doaj.art-b0314acaf3604ee882478e597eb029d7 |
| institution | Directory Open Access Journal |
| issn | 2049-9957 |
| language | English |
| last_indexed | 2024-04-12T18:18:11Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Infectious Diseases of Poverty |
| spelling | doaj.art-b0314acaf3604ee882478e597eb029d72022-12-22T03:21:32ZengBMCInfectious Diseases of Poverty2049-99572022-05-0111111610.1186/s40249-022-00987-9Assessment of echinococcosis control in Tibet Autonomous Region, ChinaLiying Wang0Quzhen Gongsang1Huasheng Pang2Min Qin3Ying Wang4Jingzhong Li5Roger Frutos6Laurent Gavotte7National Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention (Chinese Centre for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Centre for International Research On Tropical DiseasesTibet Center for Disease Control and Prevention, NHC Key Laboratory of Echinococcosis Prevention and ControlTibet Center for Disease Control and Prevention, NHC Key Laboratory of Echinococcosis Prevention and ControlNational Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention (Chinese Centre for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Centre for International Research On Tropical DiseasesNational Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention (Chinese Centre for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Centre for International Research On Tropical DiseasesTibet Center for Disease Control and Prevention, NHC Key Laboratory of Echinococcosis Prevention and ControlCirad, UMR 17, IntertrypEspace-Dev, UMR D-228, Université de MontpellierAbstract Background In China the highest prevalence of echinococcosis is in Tibet Autonomous Region (TAR). The government has issued documents and implemented comprehensive prevention and control measures focusing on controlling the source of infection of echinococcosis. It was very important to understand the implementation and effect of infectious source control measures. The purpose of this study was to examine the implementation of measures to control infectious source (domestic and stray dogs) in TAR and to assess their effectiveness. Methods We collected data on domestic dog registration and deworming and stray dog sheltering in 74 counties/districts in the TAR from 2017 to 2019. Fecal samples from domestic dogs were collected from randomly selected towns to determine Echinococcus infection in dogs using coproantigen ELISA. We analyzed the data to compare the canine rate of infection between 2016 and 2019. The data analysis was performed by SPSS statistical to compare dog infection rate in 2016 and 2019 by chi-square test, and ArcGIS was used for mapping. Results From 2017 to 2019, 84 stray dog shelters were built in TAR, and accumulatively 446,660 stray or infected dogs were arrested, sheltered, or disposed of. The number of domestic dogs went downward, with an increased registration management rate of 78.4% (2017), 88.8% (2018), and 99.0% (2019). Dogs were dewormed 5 times in 2017, 12 times in 2018, and 12 times in 2019. The dog infection rate was 1.7% (252/14,584) in 2019, significantly lower than 7.3% (552/7564) from the survey of echinococcosis prevalence in Tibet in 2016 (P < 0.05). Conclusion Between 2017 and 2019, the number of stray dogs and infection rate of Echinococcus spp. in domestic dogs decreased significantly, indicating that dogs were effectively controlled as a source of infection in TAR and reflecting a significant decrease in the risk of echinococcosis transmission. Graphical Abstracthttps://doi.org/10.1186/s40249-022-00987-9EchinococcosisHydatidosisSource of infectionControl measureEffect assessmentChina |
| spellingShingle | Liying Wang Quzhen Gongsang Huasheng Pang Min Qin Ying Wang Jingzhong Li Roger Frutos Laurent Gavotte Assessment of echinococcosis control in Tibet Autonomous Region, China Infectious Diseases of Poverty Echinococcosis Hydatidosis Source of infection Control measure Effect assessment China |
| title | Assessment of echinococcosis control in Tibet Autonomous Region, China |
| title_full | Assessment of echinococcosis control in Tibet Autonomous Region, China |
| title_fullStr | Assessment of echinococcosis control in Tibet Autonomous Region, China |
| title_full_unstemmed | Assessment of echinococcosis control in Tibet Autonomous Region, China |
| title_short | Assessment of echinococcosis control in Tibet Autonomous Region, China |
| title_sort | assessment of echinococcosis control in tibet autonomous region china |
| topic | Echinococcosis Hydatidosis Source of infection Control measure Effect assessment China |
| url | https://doi.org/10.1186/s40249-022-00987-9 |
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