Overexpression of miR-451a in sepsis and septic shock patients is involved in the regulation of sepsis-associated cardiac dysfunction and inflammation

Overexpression of miR-451a in sepsis and septic shock patients is involved in the regulation of sepsis-associated cardiac dysfunction and inflammation

Abstract The purpose of this study was to investigate the expression and clinical value of microRNA-451a (miR-451a) in septic patients and analyze its effect on sepsis-associated cardiac dysfunction and inflammation response. A rat model of sepsis was constructed by cecal ligation and puncture. The...

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Bibliographic Details
Main Authors: Heng Wang, Wenjuan Cui, Lujun Qiao, Guoxin Hu
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2020-11-01
Series:Genetics and Molecular Biology
Subjects:
MicroRNA-451
sepsis
diagnosis
inflammation
cardiac dysfunction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000600106&tlng=en

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