Gastric microbiota dysbiosis and Helicobacter pylori infection
Helicobacter pylori (H. pylori) infection is one of the most common causes of gastric disease. The persistent increase in antibiotic resistance worldwide has made H. pylori eradication challenging for clinicians. The stomach is unsterile and characterized by a unique niche. Communication among micro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1153269/full |
| _version_ | 1797856299761795072 |
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| author | Ling Zhang Ming Zhao Xiangsheng Fu |
| author_facet | Ling Zhang Ming Zhao Xiangsheng Fu |
| author_sort | Ling Zhang |
| collection | DOAJ |
| description | Helicobacter pylori (H. pylori) infection is one of the most common causes of gastric disease. The persistent increase in antibiotic resistance worldwide has made H. pylori eradication challenging for clinicians. The stomach is unsterile and characterized by a unique niche. Communication among microorganisms in the stomach results in diverse microbial fitness, population dynamics, and functional capacities, which may be positive, negative, or neutral. Here, we review gastric microecology, its imbalance, and gastric diseases. Moreover, we summarize the relationship between H. pylori and gastric microecology, including non-H. pylori bacteria, fungi, and viruses and the possibility of facilitating H. pylori eradication by gastric microecology modulation, including probiotics, prebiotics, postbiotics, synbiotics, and microbiota transplantation. |
| first_indexed | 2024-04-09T20:38:13Z |
| format | Article |
| id | doaj.art-b038a8de46c94969876e235ff6f05d98 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-09T20:38:13Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-b038a8de46c94969876e235ff6f05d982023-03-30T07:04:31ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2023-03-011410.3389/fmicb.2023.11532691153269Gastric microbiota dysbiosis and Helicobacter pylori infectionLing ZhangMing ZhaoXiangsheng FuHelicobacter pylori (H. pylori) infection is one of the most common causes of gastric disease. The persistent increase in antibiotic resistance worldwide has made H. pylori eradication challenging for clinicians. The stomach is unsterile and characterized by a unique niche. Communication among microorganisms in the stomach results in diverse microbial fitness, population dynamics, and functional capacities, which may be positive, negative, or neutral. Here, we review gastric microecology, its imbalance, and gastric diseases. Moreover, we summarize the relationship between H. pylori and gastric microecology, including non-H. pylori bacteria, fungi, and viruses and the possibility of facilitating H. pylori eradication by gastric microecology modulation, including probiotics, prebiotics, postbiotics, synbiotics, and microbiota transplantation.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1153269/fullgastric microecologygastric diseasesH. pylori eradicationbacterial interactionmicrobiota transplant |
| spellingShingle | Ling Zhang Ming Zhao Xiangsheng Fu Gastric microbiota dysbiosis and Helicobacter pylori infection Frontiers in Microbiology gastric microecology gastric diseases H. pylori eradication bacterial interaction microbiota transplant |
| title | Gastric microbiota dysbiosis and Helicobacter pylori infection |
| title_full | Gastric microbiota dysbiosis and Helicobacter pylori infection |
| title_fullStr | Gastric microbiota dysbiosis and Helicobacter pylori infection |
| title_full_unstemmed | Gastric microbiota dysbiosis and Helicobacter pylori infection |
| title_short | Gastric microbiota dysbiosis and Helicobacter pylori infection |
| title_sort | gastric microbiota dysbiosis and helicobacter pylori infection |
| topic | gastric microecology gastric diseases H. pylori eradication bacterial interaction microbiota transplant |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1153269/full |
| work_keys_str_mv | AT lingzhang gastricmicrobiotadysbiosisandhelicobacterpyloriinfection AT mingzhao gastricmicrobiotadysbiosisandhelicobacterpyloriinfection AT xiangshengfu gastricmicrobiotadysbiosisandhelicobacterpyloriinfection |