FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCER
First-line therapy for metastatic colon cancer is most important for a patient. Its median time to progression constitutes the bulk of the patient’s survival. Clearly, it is necessary to choose the most effective combinations of targeted drugs and chemotherapy regimens. The choice of therapy for pat...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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“ABV-press” Publishing house”, LLC
2015-02-01
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| Series: | Тазовая хирургия и онкология |
| Subjects: | |
| Online Access: | https://ok.abvpress.ru/jour/article/view/83 |
| _version_ | 1797757553131651072 |
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| author | M. Yu. Fedyanin A. A. Tryakin S. A. Tjulandin |
| author_facet | M. Yu. Fedyanin A. A. Tryakin S. A. Tjulandin |
| author_sort | M. Yu. Fedyanin |
| collection | DOAJ |
| description | First-line therapy for metastatic colon cancer is most important for a patient. Its median time to progression constitutes the bulk of the patient’s survival. Clearly, it is necessary to choose the most effective combinations of targeted drugs and chemotherapy regimens. The choice of therapy for patients with colon cancer is governed by both the clinical characteristics of the disease and the molecular changes of a tumor. In recent literature, there has been a great deal of evidence for the use of targeted drugs in different clinical situations; the results of comparative trials of different treatment combinations have been published. This all determines the reconsideration of the choice of a treatment regimen in patients with metastatic colon cancer; it is the topic of the present review. |
| first_indexed | 2024-03-12T18:17:25Z |
| format | Article |
| id | doaj.art-b0398439df6746dfa6092bbd1b78bec3 |
| institution | Directory Open Access Journal |
| issn | 2686-9594 |
| language | Russian |
| last_indexed | 2024-03-12T18:17:25Z |
| publishDate | 2015-02-01 |
| publisher | “ABV-press” Publishing house”, LLC |
| record_format | Article |
| series | Тазовая хирургия и онкология |
| spelling | doaj.art-b0398439df6746dfa6092bbd1b78bec32023-08-02T09:03:57Zrus“ABV-press” Publishing house”, LLCТазовая хирургия и онкология2686-95942015-02-010481510.17650/2220-3478-2014-0-4-8-1577FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCERM. Yu. Fedyanin0A. A. Tryakin1S. A. Tjulandin2N.N. Blokhin Russian Cancer Research Center, MoscowN.N. Blokhin Russian Cancer Research Center, MoscowN.N. Blokhin Russian Cancer Research Center, MoscowFirst-line therapy for metastatic colon cancer is most important for a patient. Its median time to progression constitutes the bulk of the patient’s survival. Clearly, it is necessary to choose the most effective combinations of targeted drugs and chemotherapy regimens. The choice of therapy for patients with colon cancer is governed by both the clinical characteristics of the disease and the molecular changes of a tumor. In recent literature, there has been a great deal of evidence for the use of targeted drugs in different clinical situations; the results of comparative trials of different treatment combinations have been published. This all determines the reconsideration of the choice of a treatment regimen in patients with metastatic colon cancer; it is the topic of the present review.https://ok.abvpress.ru/jour/article/view/83metastatic colon cancertargeted drugs |
| spellingShingle | M. Yu. Fedyanin A. A. Tryakin S. A. Tjulandin FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCER Тазовая хирургия и онкология metastatic colon cancer targeted drugs |
| title | FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCER |
| title_full | FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCER |
| title_fullStr | FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCER |
| title_full_unstemmed | FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCER |
| title_short | FIRST-LINE TREATMENT IN PATIENTS WITH INOPERABLE METASTATIC COLON CANCER |
| title_sort | first line treatment in patients with inoperable metastatic colon cancer |
| topic | metastatic colon cancer targeted drugs |
| url | https://ok.abvpress.ru/jour/article/view/83 |
| work_keys_str_mv | AT myufedyanin firstlinetreatmentinpatientswithinoperablemetastaticcoloncancer AT aatryakin firstlinetreatmentinpatientswithinoperablemetastaticcoloncancer AT satjulandin firstlinetreatmentinpatientswithinoperablemetastaticcoloncancer |