Chronic Urotensin-II Administration Improves Whole-Body Glucose Tolerance in High-Fat Diet-Fed Mice

Chronic Urotensin-II Administration Improves Whole-Body Glucose Tolerance in High-Fat Diet-Fed Mice

Urotensin-II (U-II) is an endogenous peptide agonist of a G protein-coupled receptor—urotensin receptor. There are many conflicting findings about the effects of U-II on blood glucose. This study aims to explore the effects of U-II on glucose metabolism in high-fat diet-fed mice. Male C57BL/6J mice...

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Bibliographic Details
Main Authors: Xi Chen, Lin Yin, Wei-hua Jia, Nuo-qi Wang, Chun-yang Xu, Bi-yu Hou, Na Li, Li Zhang, Gui-fen Qiang, Xiu-ying Yang, Guan-hua Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Endocrinology
Subjects:
urotensin-II
high-fat diet
glucose tolerance
skeletal muscle
adipose tissue
mitochondrion
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00453/full

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