Selecting synaptic partners: GRASPing the role of UNC-6/netrin

<p>Abstract</p> <p>Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in <it>Neural Development </it>describes the use of a synapse-specific label in <it>...

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Main Author: Ch'ng QueeLim
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/43
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author Ch'ng QueeLim
author_facet Ch'ng QueeLim
author_sort Ch'ng QueeLim
collection DOAJ
description <p>Abstract</p> <p>Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in <it>Neural Development </it>describes the use of a synapse-specific label in <it>Caenorhabditis elegans </it>to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets.</p> <p>See Research article: <url>http://www.neuraldevelopment.com/content/6/1/28</url></p>
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spelling doaj.art-b0405d79606c49dbb7818baf324761f12022-12-21T21:04:10ZengBMCBMC Biology1741-70072011-06-01914310.1186/1741-7007-9-43Selecting synaptic partners: GRASPing the role of UNC-6/netrinCh'ng QueeLim<p>Abstract</p> <p>Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in <it>Neural Development </it>describes the use of a synapse-specific label in <it>Caenorhabditis elegans </it>to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets.</p> <p>See Research article: <url>http://www.neuraldevelopment.com/content/6/1/28</url></p>http://www.biomedcentral.com/1741-7007/9/43
spellingShingle Ch'ng QueeLim
Selecting synaptic partners: GRASPing the role of UNC-6/netrin
BMC Biology
title Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_full Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_fullStr Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_full_unstemmed Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_short Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_sort selecting synaptic partners grasping the role of unc 6 netrin
url http://www.biomedcentral.com/1741-7007/9/43
work_keys_str_mv AT chngqueelim selectingsynapticpartnersgraspingtheroleofunc6netrin