Investigating the effects and mechanisms of Erchen Decoction in the treatment of colorectal cancer by network pharmacology and experimental validation

Investigating the effects and mechanisms of Erchen Decoction in the treatment of colorectal cancer by network pharmacology and experimental validation

Objective: Erchen Decoction (ECD), a well-known traditional Chinese medicine, exerts metabolism-regulatory, immunoregulation, and anti-tumor effects. However, the action and pharmacological mechanism of ECD remain largely unclear. In the present study, we explored the effects and mechanisms of ECD i...

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Bibliographic Details
Main Authors: Yanfei Shao, Jingxian Chen, Yujie Hu, Yuan Wu, Hualin Zeng, Shuying Lin, Qiying Lai, Xiaodong Fan, Xueliang Zhou, Minhua Zheng, Bizhen Gao, Jing Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Erchen decoction
colorectal cancer
network pharmacology
cell cycle
cell apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1000639/full

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