A human coronavirus evolves antigenically to escape antibody immunity.

There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this question by characterizing the historical evolution of human coronavirus 229E. We identify human sera from the 1980s a...

詳細記述

書誌詳細
主要な著者: Rachel T Eguia, Katharine H D Crawford, Terry Stevens-Ayers, Laurel Kelnhofer-Millevolte, Alexander L Greninger, Janet A Englund, Michael J Boeckh, Jesse D Bloom
フォーマット: 論文
言語:English
出版事項: Public Library of Science (PLoS) 2021-04-01
シリーズ:PLoS Pathogens
オンライン・アクセス:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009453&type=printable