Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conduction
ObjectivesTo characterize cervical vestibular evoked myogenic potentials (c-VEMPs) in bone conduction (BC) and air conduction (AC) in healthy children, to compare the responses to adults and to provide normative values according to age and sex.DesignObservational study in a large cohort of healthy c...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1157975/full |
| _version_ | 1797844685154156544 |
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| author | Sylvette R. Wiener-Vacher Sylvette R. Wiener-Vacher Marta Campi Priscilla Boizeau Hung Thai-Van Hung Thai-Van |
| author_facet | Sylvette R. Wiener-Vacher Sylvette R. Wiener-Vacher Marta Campi Priscilla Boizeau Hung Thai-Van Hung Thai-Van |
| author_sort | Sylvette R. Wiener-Vacher |
| collection | DOAJ |
| description | ObjectivesTo characterize cervical vestibular evoked myogenic potentials (c-VEMPs) in bone conduction (BC) and air conduction (AC) in healthy children, to compare the responses to adults and to provide normative values according to age and sex.DesignObservational study in a large cohort of healthy children (n = 118) and adults (n = 41). The c-VEMPs were normalized with the individual EMG traces, the amplitude ratios were modeled with the Royston-Wright method.ResultsIn children, the amplitude ratios of AC and BC c-VEMP were correlated (r = 0.6, p < 0.001) and their medians were not significantly different (p = 0.05). The amplitude ratio was higher in men than in women for AC (p = 0.04) and BC (p = 0.03). Children had significantly higher amplitude ratios than adults for AC (p = 0.01) and BC (p < 0.001). Normative values for children are shown. Amplitude ratio is age-dependent for AC more than for BC. Confidence limits of interaural amplitude ratio asymmetries were less than 32%. Thresholds were not different between AC and BC (88 ± 5 and 86 ± 6 dB nHL, p = 0.99). Mean latencies for AC and BC were for P-wave 13.0 and 13.2 msec and for N-wave 19.3 and 19.4 msec.ConclusionThe present study provides age- and sex-specific normative data for c-VEMP for children (6 months to 15 years of age) for AC and BC stimulation. Up to the age of 15 years, c-VEMP responses can be obtained equally well with both stimulation modes. Thus, BC represents a valid alternative for vestibular otolith testing, especially in case of air conduction disorders. |
| first_indexed | 2024-04-09T17:26:16Z |
| format | Article |
| id | doaj.art-b0416393fe4e406d9a55fc396bc07911 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-09T17:26:16Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-b0416393fe4e406d9a55fc396bc079112023-04-18T13:23:25ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-04-011410.3389/fneur.2023.11579751157975Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conductionSylvette R. Wiener-Vacher0Sylvette R. Wiener-Vacher1Marta Campi2Priscilla Boizeau3Hung Thai-Van4Hung Thai-Van5Institut de l’Audition, Institut Pasteur, CERIAH, Paris, FranceService ORL, Centre d’Exploration Fonctionnelle de l’Equilibre chez l’Enfant (EFEE), Hôpital Universitaire Robert-Debré AP-HP, Paris, FranceInstitut de l’Audition, Institut Pasteur, CERIAH, Paris, FranceUnité d’Epidémiologie Clinique, INSERM CIC1426, Hôpital Universitaire Robert-Debré AP-HP, Paris, FranceInstitut de l’Audition, Institut Pasteur, CERIAH, Paris, FranceHospices Civils de Lyon, Hôpital Edouard Herriot & Hôpital Femme Mère Enfant, Service d’Audiologie & Explorations Oto-Neurologiques, University of Lyon, Lyon, FranceObjectivesTo characterize cervical vestibular evoked myogenic potentials (c-VEMPs) in bone conduction (BC) and air conduction (AC) in healthy children, to compare the responses to adults and to provide normative values according to age and sex.DesignObservational study in a large cohort of healthy children (n = 118) and adults (n = 41). The c-VEMPs were normalized with the individual EMG traces, the amplitude ratios were modeled with the Royston-Wright method.ResultsIn children, the amplitude ratios of AC and BC c-VEMP were correlated (r = 0.6, p < 0.001) and their medians were not significantly different (p = 0.05). The amplitude ratio was higher in men than in women for AC (p = 0.04) and BC (p = 0.03). Children had significantly higher amplitude ratios than adults for AC (p = 0.01) and BC (p < 0.001). Normative values for children are shown. Amplitude ratio is age-dependent for AC more than for BC. Confidence limits of interaural amplitude ratio asymmetries were less than 32%. Thresholds were not different between AC and BC (88 ± 5 and 86 ± 6 dB nHL, p = 0.99). Mean latencies for AC and BC were for P-wave 13.0 and 13.2 msec and for N-wave 19.3 and 19.4 msec.ConclusionThe present study provides age- and sex-specific normative data for c-VEMP for children (6 months to 15 years of age) for AC and BC stimulation. Up to the age of 15 years, c-VEMP responses can be obtained equally well with both stimulation modes. Thus, BC represents a valid alternative for vestibular otolith testing, especially in case of air conduction disorders.https://www.frontiersin.org/articles/10.3389/fneur.2023.1157975/fullotolithvestibular evaluationpediatricagevestibulospinal pathwaydata modeling |
| spellingShingle | Sylvette R. Wiener-Vacher Sylvette R. Wiener-Vacher Marta Campi Priscilla Boizeau Hung Thai-Van Hung Thai-Van Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conduction Frontiers in Neurology otolith vestibular evaluation pediatric age vestibulospinal pathway data modeling |
| title | Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conduction |
| title_full | Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conduction |
| title_fullStr | Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conduction |
| title_full_unstemmed | Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conduction |
| title_short | Cervical vestibular evoked myogenic potentials in healthy children: Normative values for bone and air conduction |
| title_sort | cervical vestibular evoked myogenic potentials in healthy children normative values for bone and air conduction |
| topic | otolith vestibular evaluation pediatric age vestibulospinal pathway data modeling |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1157975/full |
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