Effect of a prebiotic supplement on knee joint function, gut microbiota, and inflammation in adults with co-morbid obesity and knee osteoarthritis: study protocol for a randomized controlled trial

Effect of a prebiotic supplement on knee joint function, gut microbiota, and inflammation in adults with co-morbid obesity and knee osteoarthritis: study protocol for a randomized controlled trial

Abstract Background Osteoarthritis (OA) is a chronic and painful condition where the articular cartilage surfaces progressively degenerate, resulting in loss of function and progressive disability. Obesity is a primary risk factor for the development and progression of knee OA, defined as the “metab...

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Bibliographic Details
Main Authors: Rafael Fortuna, David A. Hart, Keith A. Sharkey, Rachel A. Schachar, Kelly Johnston, Raylene A. Reimer
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Trials
Subjects:
Knee osteoarthritis
Gut microbiota
Knee strength
Obesity
Knee joint pain
Prebiotic
Online Access:https://doi.org/10.1186/s13063-021-05212-w

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