Influence of Serotonin Biogenic Amine on Plague Microbe Growth and Profile of its Proteins in Conditions of Cultivation on Solid Mediums
New data on stimulating effect of serotonin biogenic amine on the growth of plague microbe were obtained. A new method for Yersinia pestis isolation from material under consideration, contaminated with concomitant microflora, including environmental objects, by means of bacteriologic method was work...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2008-04-01
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| Series: | Проблемы особо опасных инфекций |
| Subjects: | |
| Online Access: | https://journal.microbe.ru/jour/article/view/1056 |
| Summary: | New data on stimulating effect of serotonin biogenic amine on the growth of plague microbe were obtained. A new method for Yersinia pestis isolation from material under consideration, contaminated with concomitant microflora, including environmental objects, by means of bacteriologic method was worked out using serotonin. This method allows reducing the periods of biological accumulation of plague etiological agent down to 24 hours, and increasing the number of colony-forming units (CFU) of plague microbe. Serotonin inhibitory effect to the synthesis of polypeptide with molecular mass of 22 kD was recognized in conditions of cultivating on Hottinger's agar (pH 7.2) at 28 °C during 24 hours. |
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| ISSN: | 0370-1069 2658-719X |