A lineage-resolved cartography of microRNA promoter activity in C. elegans empowers multidimensional developmental analysis

A lineage-resolved cartography of microRNA promoter activity in C. elegans empowers multidimensional developmental analysis

Abstract Elucidating the expression of microRNAs in developing single cells is critical for functional discovery. Here, we construct scCAMERA (single-cell cartography of microRNA expression based on reporter assay), utilizing promoter-driven fluorescent reporters in conjunction with imaging and line...

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Bibliographic Details
Main Authors: Weina Xu, Jinyi Liu, Huan Qi, Ruolin Si, Zhiguang Zhao, Zhiju Tao, Yuchuan Bai, Shipeng Hu, Xiaohan Sun, Yulin Cong, Haoye Zhang, Duchangjiang Fan, Long Xiao, Yangyang Wang, Yongbin Li, Zhuo Du
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47055-4

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