Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case report
Abstract Primary pulmonary diffuse large B‐cell lymphoma is a rare entity. We describe a case of pulmonary lymphoma with multiple nodules mimicking metastases in a treated patient with rheumatoid arthritis. A 73‐year‐old man was diagnosed with rheumatoid arthritis at the age of 30. He was treated wi...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-03-01
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| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.1111 |
| _version_ | 1797895363621814272 |
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| author | Nobuhiro Fujioka Yoshiro Kai Ryosuke Kataoka Kentaro Suzuki Kazuhiro Sakaguchi Yoshifumi Yamamoto Takeshi Kawaguchi Noriyoshi Sawabata Haruyuki Tanaka Minami Matsuoka Maiko Takeda Shigeo Muro |
| author_facet | Nobuhiro Fujioka Yoshiro Kai Ryosuke Kataoka Kentaro Suzuki Kazuhiro Sakaguchi Yoshifumi Yamamoto Takeshi Kawaguchi Noriyoshi Sawabata Haruyuki Tanaka Minami Matsuoka Maiko Takeda Shigeo Muro |
| author_sort | Nobuhiro Fujioka |
| collection | DOAJ |
| description | Abstract Primary pulmonary diffuse large B‐cell lymphoma is a rare entity. We describe a case of pulmonary lymphoma with multiple nodules mimicking metastases in a treated patient with rheumatoid arthritis. A 73‐year‐old man was diagnosed with rheumatoid arthritis at the age of 30. He was treated with leflunomide. He was followed up for a nontuberculous mycobacterial infection. He underwent percutaneous coronary intervention for acute myocardial infarction at the age of 70. In April 2022, routine follow‐up revealed new‐onset multiple nodules on chest computed tomography (CT). A position emission tomography/CT scan with 18F‐fluorodeoxyglucose showed a low‐high maximum standardized uptake value by multiple nodules. Pathologic examination of a video‐assisted thoracic surgical biopsy revealed pulmonary diffuse large B‐cell lymphoma. Systemic chemotherapy with rituximab, cyclophosphamide, vincristine, and prednisolone reduced and eliminated multiple nodules. Pulmonary lymphoma should be considered as a differential diagnosis in the case of multiple nodules on a chest CT. |
| first_indexed | 2024-04-10T07:25:25Z |
| format | Article |
| id | doaj.art-b04eb946e11348428f172d0960850c58 |
| institution | Directory Open Access Journal |
| issn | 2051-3380 |
| language | English |
| last_indexed | 2024-04-10T07:25:25Z |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj.art-b04eb946e11348428f172d0960850c582023-02-24T09:02:32ZengWileyRespirology Case Reports2051-33802023-03-01113n/an/a10.1002/rcr2.1111Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case reportNobuhiro Fujioka0Yoshiro Kai1Ryosuke Kataoka2Kentaro Suzuki3Kazuhiro Sakaguchi4Yoshifumi Yamamoto5Takeshi Kawaguchi6Noriyoshi Sawabata7Haruyuki Tanaka8Minami Matsuoka9Maiko Takeda10Shigeo Muro11Department of Respiratory Medicine Nara Medical University Nara JapanDepartment of Respiratory Medicine Minami‐Nara General Medical Center Nara JapanDepartment of Respiratory Medicine Minami‐Nara General Medical Center Nara JapanDepartment of Respiratory Medicine Minami‐Nara General Medical Center Nara JapanDepartment of Respiratory Medicine Nara Medical University Nara JapanDepartment of Respiratory Medicine Nara Medical University Nara JapanDepartment of Thoracic and Cardiovascular Surgery Nara Medical University Nara JapanDepartment of Thoracic and Cardiovascular Surgery Nara Medical University Nara JapanDepartment of Haematology Nara Medical University Nara JapanDepartment of Diagnostic Pathology Nara Medical University Nara JapanDepartment of Diagnostic Pathology Nara Medical University Nara JapanDepartment of Respiratory Medicine Nara Medical University Nara JapanAbstract Primary pulmonary diffuse large B‐cell lymphoma is a rare entity. We describe a case of pulmonary lymphoma with multiple nodules mimicking metastases in a treated patient with rheumatoid arthritis. A 73‐year‐old man was diagnosed with rheumatoid arthritis at the age of 30. He was treated with leflunomide. He was followed up for a nontuberculous mycobacterial infection. He underwent percutaneous coronary intervention for acute myocardial infarction at the age of 70. In April 2022, routine follow‐up revealed new‐onset multiple nodules on chest computed tomography (CT). A position emission tomography/CT scan with 18F‐fluorodeoxyglucose showed a low‐high maximum standardized uptake value by multiple nodules. Pathologic examination of a video‐assisted thoracic surgical biopsy revealed pulmonary diffuse large B‐cell lymphoma. Systemic chemotherapy with rituximab, cyclophosphamide, vincristine, and prednisolone reduced and eliminated multiple nodules. Pulmonary lymphoma should be considered as a differential diagnosis in the case of multiple nodules on a chest CT.https://doi.org/10.1002/rcr2.1111diffuse large B cellmultiple lung nodulesprimary pulmonary lymphoma |
| spellingShingle | Nobuhiro Fujioka Yoshiro Kai Ryosuke Kataoka Kentaro Suzuki Kazuhiro Sakaguchi Yoshifumi Yamamoto Takeshi Kawaguchi Noriyoshi Sawabata Haruyuki Tanaka Minami Matsuoka Maiko Takeda Shigeo Muro Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case report Respirology Case Reports diffuse large B cell multiple lung nodules primary pulmonary lymphoma |
| title | Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case report |
| title_full | Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case report |
| title_fullStr | Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case report |
| title_full_unstemmed | Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case report |
| title_short | Primary pulmonary diffuse large B‐cell lymphoma presenting multiple nodules mimicking metastasis: A case report |
| title_sort | primary pulmonary diffuse large b cell lymphoma presenting multiple nodules mimicking metastasis a case report |
| topic | diffuse large B cell multiple lung nodules primary pulmonary lymphoma |
| url | https://doi.org/10.1002/rcr2.1111 |
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