Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis

Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis

Leptomeningeal metastases from solid tumors are a rare complication with a very poor prognosis. Here the authors report the efficacy and safety of combined ipilimumab and nivolumab in patients with leptomeningeal carcinomatosis.

Dettagli Bibliografici
Autori principali:	Priscilla K. Brastianos, Matthew R. Strickland, Eudocia Quant Lee, Nancy Wang, Justine V. Cohen, Ugonma Chukwueke, Deborah Anne Forst, April Eichler, Beth Overmoyer, Nancy U. Lin, Wendy Y. Chen, Aditya Bardia, Dejan Juric, Ibiayi Dagogo-Jack, Michael D. White, Jorg Dietrich, Naema Nayyar, Albert E. Kim, Christopher Alvarez-Breckenridge, Maura Mahar, Joana L. Mora, Brian V. Nahed, Pamela S. Jones, Helen A. Shih, Elizabeth R. Gerstner, Anita Giobbie-Hurder, Scott L. Carter, Kevin Oh, Daniel P. Cahill, Ryan J. Sullivan
Natura:	Articolo
Lingua:	English
Pubblicazione:	Nature Portfolio 2021-10-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-021-25859-y

Documenti analoghi

Leptomeningeal carcinomatosis or ischemic cerebrovascular disease?
di: Ayelet Eran, et al.
Pubblicazione: (2021-05-01)

Leptomeningeal Carcinomatosis with Delayed Ocular Manifestations
di: Craig Czyz, et al.
Pubblicazione: (2021-02-01)

Multiple Dural Tuberculomas Presenting as Leptomeningeal Carcinomatosis
di: Hasan Kocaeli, et al.
Pubblicazione: (2011-01-01)

Literature Review: Role of Neurosurgery in Leptomeningeal Carcinomatosis
di: Thaís Mitie Ogasawara, et al.
Pubblicazione: (2023-12-01)

Leptomeningeal Carcinomatosis in a Patient with Ovarian Cancer
di: Özlem Kayım Yıldız
Pubblicazione: (2019-09-01)

Leptomeningeal carcinomatosis in small cell carcinoma of the prostate
di: Kyotaro Fukuta, et al.
Pubblicazione: (2022-11-01)

Leptomeningeal carcinomatosis in a patient with gallbladder carcinoma
di: Nisha Jose, et al.
Pubblicazione: (2017-01-01)

Leptomeningeal Carcinomatosis of Metastatic Primary Prostate Cancer
di: Daniel Stenberg, et al.
Pubblicazione: (2021-06-01)

Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas
di: Priscilla K. Brastianos, et al.
Pubblicazione: (2022-03-01)

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases
di: Prakadan, Sanjay M, et al.
Pubblicazione: (2022)

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases
di: Sanjay M. Prakadan, et al.
Pubblicazione: (2021-10-01)

Meta-analysis of commonly mutated genes in leptomeningeal carcinomatosis
di: Irem Congur, et al.
Pubblicazione: (2023-04-01)

Leptomeningeal Carcinomatosis: A Clinical Dilemma in Neuroendocrine Neoplasms
di: Leonidas Apostolidis, et al.
Pubblicazione: (2021-03-01)

Leptomeningeal carcinomatosis can be presenting manifestation of breast carcinoma
di: Mandić-Stojmenović Gorana, et al.
Pubblicazione: (2016-01-01)

Complete response of leptomeningeal carcinomatosis secondary to breast cancer
di: Idriss Troussier, et al.
Pubblicazione: (2020-12-01)

Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
di: Maria Vergoulidou
Pubblicazione: (2017-03-01)

Author Correction: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases
di: Sanjay M. Prakadan, et al.
Pubblicazione: (2021-11-01)

Response assessment in metastatic melanoma treated with ipilimumab and bevacizumab: CT tumor size and density as markers for response and outcome
di: F Stephen Hodi, et al.
Pubblicazione: (2014-11-01)

Complete Eye Ophthalmoplegia: the unusual initial presentation of Leptomeningeal Carcinomatosis
di: Lakshpaul Chauhan, et al.
Pubblicazione: (2019-07-01)

Clinical outcome of cerebrospinal fluid shunts in patients with leptomeningeal carcinomatosis
di: Hye Seon Kim, et al.
Pubblicazione: (2019-03-01)

Central retinal vein occlusion as the initial presentation in leptomeningeal carcinomatosis
di: Anusha Venkataraman, et al.
Pubblicazione: (2016-01-01)

Inflammatory demyelinating polyneuropathy versus leptomeningeal disease following Ipilimumab
di: Lorraine Cafuir, et al.
Pubblicazione: (2018-01-01)

Leptomeningeal Carcinomatosis in a Patient with Pancreatic Cancer: A Rare Phenomenon?
di: Taichi Sayanagi, et al.
Pubblicazione: (2022-07-01)

The Importance of Cerebrospinal Fluid Cytology in Leptomeningeal Carcinomatosis Presenting with Intracranial Hypertension
di: Sibel Karaca, et al.
Pubblicazione: (2006-04-01)

Leptomeningeal Carcinomatosis Mimicking Idiopathic Intracranial Hypertension with Transverse Sinus Stenosis
di: Hyung Geun Oh
Pubblicazione: (2014-12-01)

A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
di: Park Kwang-Kuk, et al.
Pubblicazione: (2012-05-01)

Cauda Equina Syndrome Secondary to Leptomeningeal Carcinomatosis of Gastroesophageal Junction Cancer
di: Amal Alkhotani, et al.
Pubblicazione: (2016-04-01)

A Case of Isolated Leptomeningeal Carcinomatosis from Advanced Gastric Cancer
di: Jung Geun Ji, et al.
Pubblicazione: (2016-08-01)

A case report of prostate adenocarcinoma with leptomeningeal carcinomatosis and intracerebral metastasis
di: Danial Fazilat‐Panah, et al.
Pubblicazione: (2021-10-01)

Leptomeningeal Carcinomatosis: A Call for Optimizing Diagnostic Sensitivity by the Hematology Laboratory
di: Benjamin Lardinois, et al.
Pubblicazione: (2021-08-01)

A Case of Leptomeningeal Carcinomatosis from Aggressive Metastatic Prostate Cancer
di: Ryan David Carroll, et al.
Pubblicazione: (2019-04-01)

Isolated leptomeningeal carcinomatosis and possible fungal meningitis as late sequelae of oesophageal adenocarcinoma
di: Dumbill, R, et al.
Pubblicazione: (2019)

Malignant transformation and subsequent leptomeningeal carcinomatosis of a gastric polyp in a dog
di: Dillon S. Didehvar, et al.
Pubblicazione: (2024-05-01)

Leptomeningeal Carcinomatosis Secondary to Gastroesophageal Adenocarcinoma: A Case Report and Review of the Literature
di: Ayman A Abdo, et al.
Pubblicazione: (2002-01-01)

Leptomeningeal carcinomatosis from breast cancer initially mimicking cerebral infarction on MRI
di: Nozomi Satani, MD, et al.
Pubblicazione: (2024-08-01)

Blindness due to leptomeningeal carcinomatosis as an initial manifestation of recurrent acute lymphoblastic leukemia
di: Ya-Chi Huang, et al.
Pubblicazione: (2019-01-01)

Palliative Radiotherapy for Leptomeningeal Carcinomatosis–Analysis of Outcome, Prognostic Factors, and Symptom Response
di: Rami A. El Shafie, et al.
Pubblicazione: (2019-01-01)

Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
di: Martin Krupa, MD, et al.
Pubblicazione: (2017-06-01)

Nonconvulsive status epilepticus associated with leptomeningeal carcinomatosis and positive SOX1 antibodies
di: Jeong Yeon Kim, et al.
Pubblicazione: (2020-06-01)

Endocrine therapy for the treatment of leptomeningeal carcinomatosis in luminal breast cancer: a comprehensive review
di: Leonor Fernandes, et al.
Pubblicazione: (2020-12-01)