Hepatocyte Growth Factor Mediates the Antifibrogenic Action of Ocimum bacilicum Essential Oil against CCl4-Induced Liver Fibrosis in Rats

Hepatocyte Growth Factor Mediates the Antifibrogenic Action of Ocimum bacilicum Essential Oil against CCl4-Induced Liver Fibrosis in Rats

The current investigation aimed to evaluate the antifibrogenic potential of Ocimum basilicum essential oil (OBE) and further to explore some of its underlying mechanisms. Three groups of rats were used: group I (control), group II (CCl4 model) and group III (OBE-treated) received CCl4 and OBE 2 week...

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Bibliographic Details
Main Authors: Hanan A. Ogaly, Nadia A. Eltablawy, Adel M. El-Behairy, Hatim El-Hindi, Reham M. Abd-Elsalam
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
Ocimum basilicum
liver fibrosis
antioxidant
α-SMA
CYP2E1
HGF
Online Access:http://www.mdpi.com/1420-3049/20/8/13518

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