PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products

PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products

Abstract Osteoblast apoptosis plays an important role in age-related bone loss and osteoporosis. Our previous study revealed that advanced oxidation protein products (AOPPs) could induce nicotinamide adenine dinucleotide phosphate oxidase (NOX)-derived reactive oxygen species (ROS) production, cause...

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Bibliographic Details
Main Authors:	Wei Li, Wang-Sheng Jiang, Ya-Ru Su, Ke-Wu Tu, Lin Zou, Cong-Rui Liao, Qian Wu, Zi-Han Wang, Zhao-Ming Zhong, Jian-Ting Chen, Si-Yuan Zhu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-02-01
Series:	Cell Death and Disease
Online Access:	https://doi.org/10.1038/s41419-023-05595-5

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