The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens
Abstract Background Selenium (Se) is an essential trace mineral in broilers, which has several important roles in biological processes. Organic forms of Se are more efficient than inorganic forms and can be produced biologically via Se microbial reduction. Hence, the possibility of using Se-enriched...
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| Format: | Article |
| Language: | English |
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BMC
2017-08-01
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| Series: | BMC Veterinary Research |
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| Online Access: | http://link.springer.com/article/10.1186/s12917-017-1159-4 |
| _version_ | 1818969353295495168 |
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| author | A. M. Dalia T. C. Loh A. Q. Sazili M. F. Jahromi A. A. Samsudin |
| author_facet | A. M. Dalia T. C. Loh A. Q. Sazili M. F. Jahromi A. A. Samsudin |
| author_sort | A. M. Dalia |
| collection | DOAJ |
| description | Abstract Background Selenium (Se) is an essential trace mineral in broilers, which has several important roles in biological processes. Organic forms of Se are more efficient than inorganic forms and can be produced biologically via Se microbial reduction. Hence, the possibility of using Se-enriched bacteria as feed supplement may provide an interesting source of organic Se, and benefit broiler antioxidant system and other biological processes. The objective of this study was to examine the impacts of inorganic Se and different bacterial organic Se sources on the performance, serum and tissues Se status, antioxidant capacity, and liver mRNA expression of selenoproteins in broilers. Results Results indicated that different Se sources did not significantly (P ≤ 0.05) affect broiler growth performance. However, bacterial organic Se of T5 (basal diet +0.3 mg /kg feed ADS18 Se), T4 (basal diet +0.3 mg /kg feed ADS2 Se), and T3 (basal diet +0.3 mg /kg feed ADS1 Se) exhibited significantly (P ≤ 0.05) highest Se concentration in serum, liver, and kidney respectively. Dietary inorganic Se and bacterial organic Se were observed to significantly affect broiler serum ALT, AST, LDH activities and serum creatinine level. ADS18 supplemented Se of (Stenotrophomonas maltophilia) bacterial strain showed the highest GSH-Px activity with the lowest MDA content in serum, and the highest GSH-Px and catalase activity in the kidney, while bacterial Se of ADS2 (Klebsiella pneumoniae) resulted in a higher level of GSH-Px1 and catalase in liver. Moreover, our study showed that in comparison with sodium selenite, only ADS18 bacterial Se showed a significantly higher mRNA level in GSH-Px1, GSH-Px4, DIO1, and TXNDR1, while both ADS18 and ADS2 showed high level of mRNA of DIO2 compared to sodium selenite. Conclusions The supplementation of bacterial organic Se in broiler chicken, improved tissue Se deposition, antioxidant status, and selenoproteins gene expression, and can be considered as an effective alternative source of Se in broiler chickens. |
| first_indexed | 2024-12-20T14:19:14Z |
| format | Article |
| id | doaj.art-b051a414417a4ee19fa1964d8b88c71d |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-20T14:19:14Z |
| publishDate | 2017-08-01 |
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| spelling | doaj.art-b051a414417a4ee19fa1964d8b88c71d2022-12-21T19:37:57ZengBMCBMC Veterinary Research1746-61482017-08-0113111110.1186/s12917-017-1159-4The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickensA. M. Dalia0T. C. Loh1A. Q. Sazili2M. F. Jahromi3A. A. Samsudin4Department of Animal Science, Faculty of Agriculture, Universiti Putra MalaysiaDepartment of Animal Science, Faculty of Agriculture, Universiti Putra MalaysiaDepartment of Animal Science, Faculty of Agriculture, Universiti Putra MalaysiaInstitute of Tropical Agriculture, Universiti Putra MalaysiaDepartment of Animal Science, Faculty of Agriculture, Universiti Putra MalaysiaAbstract Background Selenium (Se) is an essential trace mineral in broilers, which has several important roles in biological processes. Organic forms of Se are more efficient than inorganic forms and can be produced biologically via Se microbial reduction. Hence, the possibility of using Se-enriched bacteria as feed supplement may provide an interesting source of organic Se, and benefit broiler antioxidant system and other biological processes. The objective of this study was to examine the impacts of inorganic Se and different bacterial organic Se sources on the performance, serum and tissues Se status, antioxidant capacity, and liver mRNA expression of selenoproteins in broilers. Results Results indicated that different Se sources did not significantly (P ≤ 0.05) affect broiler growth performance. However, bacterial organic Se of T5 (basal diet +0.3 mg /kg feed ADS18 Se), T4 (basal diet +0.3 mg /kg feed ADS2 Se), and T3 (basal diet +0.3 mg /kg feed ADS1 Se) exhibited significantly (P ≤ 0.05) highest Se concentration in serum, liver, and kidney respectively. Dietary inorganic Se and bacterial organic Se were observed to significantly affect broiler serum ALT, AST, LDH activities and serum creatinine level. ADS18 supplemented Se of (Stenotrophomonas maltophilia) bacterial strain showed the highest GSH-Px activity with the lowest MDA content in serum, and the highest GSH-Px and catalase activity in the kidney, while bacterial Se of ADS2 (Klebsiella pneumoniae) resulted in a higher level of GSH-Px1 and catalase in liver. Moreover, our study showed that in comparison with sodium selenite, only ADS18 bacterial Se showed a significantly higher mRNA level in GSH-Px1, GSH-Px4, DIO1, and TXNDR1, while both ADS18 and ADS2 showed high level of mRNA of DIO2 compared to sodium selenite. Conclusions The supplementation of bacterial organic Se in broiler chicken, improved tissue Se deposition, antioxidant status, and selenoproteins gene expression, and can be considered as an effective alternative source of Se in broiler chickens.http://link.springer.com/article/10.1186/s12917-017-1159-4BroilerSeleniumOrganicBacteriaAntioxidantSelenoprotein |
| spellingShingle | A. M. Dalia T. C. Loh A. Q. Sazili M. F. Jahromi A. A. Samsudin The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens BMC Veterinary Research Broiler Selenium Organic Bacteria Antioxidant Selenoprotein |
| title | The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens |
| title_full | The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens |
| title_fullStr | The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens |
| title_full_unstemmed | The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens |
| title_short | The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens |
| title_sort | effect of dietary bacterial organic selenium on growth performance antioxidant capacity and selenoproteins gene expression in broiler chickens |
| topic | Broiler Selenium Organic Bacteria Antioxidant Selenoprotein |
| url | http://link.springer.com/article/10.1186/s12917-017-1159-4 |
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