Usher syndrome proteins ADGRV1 (USH2C) and CIB2 (USH1J) interact and share a common interactome containing TRiC/CCT-BBS chaperonins

The human Usher syndrome (USH) is the most common form of a sensory hereditary ciliopathy characterized by progressive vision and hearing loss. Mutations in the genes ADGRV1 and CIB2 have been associated with two distinct sub-types of USH, namely, USH2C and USH1J. The proteins encoded by the two gen...

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Những tác giả chính: Joshua Linnert, Barbara Knapp, Baran E. Güler, Karsten Boldt, Marius Ueffing, Uwe Wolfrum
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Frontiers Media S.A. 2023-06-01
Loạt:Frontiers in Cell and Developmental Biology
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Truy cập trực tuyến:https://www.frontiersin.org/articles/10.3389/fcell.2023.1199069/full