Probe-based confocal laser endomicroscopy in diagnosis of desquamative interstitial pneumonia in nonsmoker

Desquamative interstitial pneumonia is a rare disease that is predominantly associated with smoking. Surgical biopsy is usually recommended for the diagnosis of this disorder. Probe-based confocal laser endomicroscopy (pCLE) is a new method of minimally invasive in vivo microscopic image of airways...

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Bibliographic Details
Main Authors: Igor S. Mamenko, Igor V. Vasilev, Irina A. Tabanakova, Sultan M. Gasanmagomedov, Vera V. Sysoeva, Alexey D. Ushkov, Tatiana A. Novickaya, Piotr K. Yablonskii
Format: Article
Language:English
Published: PAGEPress Publications 2019-09-01
Series:Monaldi Archives for Chest Disease
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Online Access:https://www.monaldi-archives.org/index.php/macd/article/view/1052
Description
Summary:Desquamative interstitial pneumonia is a rare disease that is predominantly associated with smoking. Surgical biopsy is usually recommended for the diagnosis of this disorder. Probe-based confocal laser endomicroscopy (pCLE) is a new method of minimally invasive in vivo microscopic image of airways and alveoli. We use this method for desquamative interstitial pneumonia in nonsmoker. The pCLE image shows thickened intra-alveolar septae and clusters of autofluorescent cells within the alveoli, which is unusual for non-smoking patients. We think this pattern can be used for differential diagnosis of desquamative interstitial pneumonia in nonsmokers.
ISSN:1122-0643
2532-5264