Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine

mRNA vaccines have been shown to prevent SARS-CoV-2 infection and reduce hospitalization and mortality rates. Here, the authors show evidence of long-term memory CD8 + T cells in individuals who received the BNT162b2 SARS-CoV-2 mRNA vaccine.

Bibliographic Details
Main Authors: Nozomi Kuse, Yu Zhang, Takayuki Chikata, Hung The Nguyen, Shinichi Oka, Hiroyuki Gatanaga, Masafumi Takiguchi
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32989-4
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author Nozomi Kuse
Yu Zhang
Takayuki Chikata
Hung The Nguyen
Shinichi Oka
Hiroyuki Gatanaga
Masafumi Takiguchi
author_facet Nozomi Kuse
Yu Zhang
Takayuki Chikata
Hung The Nguyen
Shinichi Oka
Hiroyuki Gatanaga
Masafumi Takiguchi
author_sort Nozomi Kuse
collection DOAJ
description mRNA vaccines have been shown to prevent SARS-CoV-2 infection and reduce hospitalization and mortality rates. Here, the authors show evidence of long-term memory CD8 + T cells in individuals who received the BNT162b2 SARS-CoV-2 mRNA vaccine.
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spelling doaj.art-b059fd47ef9e4e3e945a1bbbe348a7102022-12-22T03:12:55ZengNature PortfolioNature Communications2041-17232022-09-0113111110.1038/s41467-022-32989-4Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccineNozomi Kuse0Yu Zhang1Takayuki Chikata2Hung The Nguyen3Shinichi Oka4Hiroyuki Gatanaga5Masafumi Takiguchi6Division of International Collaboration Research and Tokyo laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto UniversityDivision of International Collaboration Research and Tokyo laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto UniversityDivision of International Collaboration Research and Tokyo laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto UniversityDivision of International Collaboration Research and Tokyo laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto UniversityDivision of International Collaboration Research and Tokyo laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto UniversityDivision of International Collaboration Research and Tokyo laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto UniversityDivision of International Collaboration Research and Tokyo laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto UniversitymRNA vaccines have been shown to prevent SARS-CoV-2 infection and reduce hospitalization and mortality rates. Here, the authors show evidence of long-term memory CD8 + T cells in individuals who received the BNT162b2 SARS-CoV-2 mRNA vaccine.https://doi.org/10.1038/s41467-022-32989-4
spellingShingle Nozomi Kuse
Yu Zhang
Takayuki Chikata
Hung The Nguyen
Shinichi Oka
Hiroyuki Gatanaga
Masafumi Takiguchi
Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine
Nature Communications
title Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine
title_full Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine
title_fullStr Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine
title_full_unstemmed Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine
title_short Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine
title_sort long term memory cd8 t cells specific for sars cov 2 in individuals who received the bnt162b2 mrna vaccine
url https://doi.org/10.1038/s41467-022-32989-4
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