Feasibility of Multiple Micro-Particle Trapping—A Simulation Study
Both optical tweezers and acoustic tweezers have been demonstrated for trapping small particles in diverse biomedical applications. Compared to the optical tweezers, acoustic tweezers have deeper penetration, lower intensity, and are more useful in light opaque media. These advantages enable the pot...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-02-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/15/3/4958 |
| _version_ | 1828371817181478912 |
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| author | Yanyan Yu Weibao Qiu Bernard Chiu Lei Sun |
| author_facet | Yanyan Yu Weibao Qiu Bernard Chiu Lei Sun |
| author_sort | Yanyan Yu |
| collection | DOAJ |
| description | Both optical tweezers and acoustic tweezers have been demonstrated for trapping small particles in diverse biomedical applications. Compared to the optical tweezers, acoustic tweezers have deeper penetration, lower intensity, and are more useful in light opaque media. These advantages enable the potential utility of acoustic tweezers in biological science. Since the first demonstration of acoustic tweezers, various applications have required the trapping of not only one, but more particles simultaneously in both the axial and lateral direction. In this research, a method is proposed to create multiple trapping patterns, to prove the feasibility of trapping micro-particles. It has potential ability to electronically control the location and movement of the particles in real-time. A multiple-focus acoustic field can be generated by controlling the excitation of the transducer elements. The pressure and intensity of the field are obtained by modeling phased array transducer. Moreover, scattering force and gradient force at various positions are also evaluated to analyze their relative components to the effect of the acoustic tweezers. Besides, the axial and lateral radiation force and the trapping trajectory are computed based on ray acoustic approach. The results obtained demonstrate that the acoustic tweezers are capable of multiple trapping in both the axial and lateral directions. |
| first_indexed | 2024-04-14T06:54:34Z |
| format | Article |
| id | doaj.art-b05cddc1c5a746f896479cfd1733d325 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-14T06:54:34Z |
| publishDate | 2015-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-b05cddc1c5a746f896479cfd1733d3252022-12-22T02:06:56ZengMDPI AGSensors1424-82202015-02-011534958497410.3390/s150304958s150304958Feasibility of Multiple Micro-Particle Trapping—A Simulation StudyYanyan Yu0Weibao Qiu1Bernard Chiu2Lei Sun3Department of Electronic Engineering, City University of Hong Kong, Hong Kong, ChinaPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, ChinaDepartment of Electronic Engineering, City University of Hong Kong, Hong Kong, ChinaInterdisciplinary Division of Biomedical Engineering, the Hong Kong Polytechnic University, Hong Kong, ChinaBoth optical tweezers and acoustic tweezers have been demonstrated for trapping small particles in diverse biomedical applications. Compared to the optical tweezers, acoustic tweezers have deeper penetration, lower intensity, and are more useful in light opaque media. These advantages enable the potential utility of acoustic tweezers in biological science. Since the first demonstration of acoustic tweezers, various applications have required the trapping of not only one, but more particles simultaneously in both the axial and lateral direction. In this research, a method is proposed to create multiple trapping patterns, to prove the feasibility of trapping micro-particles. It has potential ability to electronically control the location and movement of the particles in real-time. A multiple-focus acoustic field can be generated by controlling the excitation of the transducer elements. The pressure and intensity of the field are obtained by modeling phased array transducer. Moreover, scattering force and gradient force at various positions are also evaluated to analyze their relative components to the effect of the acoustic tweezers. Besides, the axial and lateral radiation force and the trapping trajectory are computed based on ray acoustic approach. The results obtained demonstrate that the acoustic tweezers are capable of multiple trapping in both the axial and lateral directions.http://www.mdpi.com/1424-8220/15/3/4958acoustic tweezersmultiple trappingphased array transducer |
| spellingShingle | Yanyan Yu Weibao Qiu Bernard Chiu Lei Sun Feasibility of Multiple Micro-Particle Trapping—A Simulation Study Sensors acoustic tweezers multiple trapping phased array transducer |
| title | Feasibility of Multiple Micro-Particle Trapping—A Simulation Study |
| title_full | Feasibility of Multiple Micro-Particle Trapping—A Simulation Study |
| title_fullStr | Feasibility of Multiple Micro-Particle Trapping—A Simulation Study |
| title_full_unstemmed | Feasibility of Multiple Micro-Particle Trapping—A Simulation Study |
| title_short | Feasibility of Multiple Micro-Particle Trapping—A Simulation Study |
| title_sort | feasibility of multiple micro particle trapping a simulation study |
| topic | acoustic tweezers multiple trapping phased array transducer |
| url | http://www.mdpi.com/1424-8220/15/3/4958 |
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