Lysosomal Storage Diseases
Lysosomal storage diseases are a group of inherited and acquired disorders. They are characterized by interruption of recycling of cellular and extracellular molecules. Clinically, they are presented as developmental and neurological symptoms similar to other inherited and acquired disorders. This a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SciELO
2014-03-01
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| Series: | Journal of Inborn Errors of Metabolism and Screening |
| Online Access: | https://doi.org/10.1177/2326409813517663 |
| _version_ | 1828815391741181952 |
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| author | Joseph Alroy DVM, DACVP Jeremiah A. Lyons MVB, PhD, DACVP |
| author_facet | Joseph Alroy DVM, DACVP Jeremiah A. Lyons MVB, PhD, DACVP |
| author_sort | Joseph Alroy DVM, DACVP |
| collection | DOAJ |
| description | Lysosomal storage diseases are a group of inherited and acquired disorders. They are characterized by interruption of recycling of cellular and extracellular molecules. Clinically, they are presented as developmental and neurological symptoms similar to other inherited and acquired disorders. This article reviews the function of lysosomes, the current mechanisms that cause the interruption of recycling, the consequences that are manifested clinically, and the methods to diagnose these disorders. |
| first_indexed | 2024-12-12T10:43:25Z |
| format | Article |
| id | doaj.art-b05d92653c084761901a9c323f0e9b37 |
| institution | Directory Open Access Journal |
| issn | 2326-4594 |
| language | English |
| last_indexed | 2024-12-12T10:43:25Z |
| publishDate | 2014-03-01 |
| publisher | SciELO |
| record_format | Article |
| series | Journal of Inborn Errors of Metabolism and Screening |
| spelling | doaj.art-b05d92653c084761901a9c323f0e9b372022-12-22T00:26:58ZengSciELOJournal of Inborn Errors of Metabolism and Screening2326-45942014-03-01210.1177/232640981351766310.1177_2326409813517663Lysosomal Storage DiseasesJoseph Alroy DVM, DACVP0Jeremiah A. Lyons MVB, PhD, DACVP1Department of Biomedical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USADepartment of Biomedical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USALysosomal storage diseases are a group of inherited and acquired disorders. They are characterized by interruption of recycling of cellular and extracellular molecules. Clinically, they are presented as developmental and neurological symptoms similar to other inherited and acquired disorders. This article reviews the function of lysosomes, the current mechanisms that cause the interruption of recycling, the consequences that are manifested clinically, and the methods to diagnose these disorders.https://doi.org/10.1177/2326409813517663 |
| spellingShingle | Joseph Alroy DVM, DACVP Jeremiah A. Lyons MVB, PhD, DACVP Lysosomal Storage Diseases Journal of Inborn Errors of Metabolism and Screening |
| title | Lysosomal Storage Diseases |
| title_full | Lysosomal Storage Diseases |
| title_fullStr | Lysosomal Storage Diseases |
| title_full_unstemmed | Lysosomal Storage Diseases |
| title_short | Lysosomal Storage Diseases |
| title_sort | lysosomal storage diseases |
| url | https://doi.org/10.1177/2326409813517663 |
| work_keys_str_mv | AT josephalroydvmdacvp lysosomalstoragediseases AT jeremiahalyonsmvbphddacvp lysosomalstoragediseases |