Histopathological spectrum of lung findings in autopsy cases
Background: The incidence of lung pathology is the most common autopsy finding and is responsible for a great deal of mortality and morbidity. It is affected by a wide variety of respiratory pathogens and is involved in many systemic diseases. It is secondarily involved in almost all forms of termin...
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| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2024-01-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/57717 |
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| author | Gowri Prakasam Brihadisvarar Sadasivam Vallabi Rajasekaran Kavitha Muniraj Abikarthiga Prathapan |
| author_facet | Gowri Prakasam Brihadisvarar Sadasivam Vallabi Rajasekaran Kavitha Muniraj Abikarthiga Prathapan |
| author_sort | Gowri Prakasam |
| collection | DOAJ |
| description | Background: The incidence of lung pathology is the most common autopsy finding and is responsible for a great deal of mortality and morbidity. It is affected by a wide variety of respiratory pathogens and is involved in many systemic diseases. It is secondarily involved in almost all forms of terminal disease. Radiological findings are usually nonspecific in lung diseases and need prompt histopathological examination to find out the exact cause of death.
Aims and Objectives: The aim is to study the spectrum of histopathological findings in lung in autopsy cases.
Materials and Methods: This is a retrospective study done in the Department of Pathology at Government Kilpauk Medical College and Hospital during the year 2022. Lung specimens were received from the Forensic medicine department. Gross findings were noted. Following adequate formalin fixation, the tissue specimens were processed and paraffin sectioning was done followed by hematoxylin and eosin staining. The findings were documented and the results were analyzed.
Results: Among 100 cases studied during year maximum cases were seen in the age group of 31–40 years (32%). Males (72%) were more commonly affected than females (28%). The most common findings are Pulmonary edema (34%) followed by congestion (32%) and other findings include emphysematous change (13%), pneumonia (10%), tuberculosis (6%), metastatic adenocarcinomatous deposits (1%), primary well-differentiated adenocarcinoma (1%), pulmonary chondroma (1%), and bronchiectasis (1%).
Conclusion: The most common finding observed was pulmonary edema. In our study, male preponderance was noted. This study emphasizes to scrutinize the histopathological findings in the lung, especially following a sudden death. |
| first_indexed | 2024-03-08T17:30:00Z |
| format | Article |
| id | doaj.art-b062d1028f91458886fe9104c44f936b |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-03-08T17:30:00Z |
| publishDate | 2024-01-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-b062d1028f91458886fe9104c44f936b2024-01-02T16:25:30ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762024-01-01151204208https://doi.org/10.3126/ajms.v15i1.57717Histopathological spectrum of lung findings in autopsy casesGowri Prakasam 0https://orcid.org/0009-0004-8999-2428Brihadisvarar Sadasivam 1Vallabi Rajasekaran 2Kavitha Muniraj 3https://orcid.org/0009-0004-9836-8598Abikarthiga Prathapan 4https://orcid.org/0009-0009-8329-9637Assistant Professor, Department of Pathology, Government Kilpauk Medical College and Hospital, Kilpauk, Tamil Nadu, India Assistant Professor, Department of Pathology, Government Kilpauk Medical College and Hospital, Kilpauk, Tamil Nadu, IndiaAssistant Professor, Department of Pathology, Government Kilpauk Medical College and Hospital, Kilpauk, Tamil Nadu, IndiaAssistant Professor, Department of Pathology, Government Kilpauk Medical College and Hospital, Kilpauk, Tamil Nadu, IndiaPostgraduate Resident, Department of Pathology, Government Kilpauk Medical College and Hospital, Kilpauk, Tamil Nadu, India Background: The incidence of lung pathology is the most common autopsy finding and is responsible for a great deal of mortality and morbidity. It is affected by a wide variety of respiratory pathogens and is involved in many systemic diseases. It is secondarily involved in almost all forms of terminal disease. Radiological findings are usually nonspecific in lung diseases and need prompt histopathological examination to find out the exact cause of death. Aims and Objectives: The aim is to study the spectrum of histopathological findings in lung in autopsy cases. Materials and Methods: This is a retrospective study done in the Department of Pathology at Government Kilpauk Medical College and Hospital during the year 2022. Lung specimens were received from the Forensic medicine department. Gross findings were noted. Following adequate formalin fixation, the tissue specimens were processed and paraffin sectioning was done followed by hematoxylin and eosin staining. The findings were documented and the results were analyzed. Results: Among 100 cases studied during year maximum cases were seen in the age group of 31–40 years (32%). Males (72%) were more commonly affected than females (28%). The most common findings are Pulmonary edema (34%) followed by congestion (32%) and other findings include emphysematous change (13%), pneumonia (10%), tuberculosis (6%), metastatic adenocarcinomatous deposits (1%), primary well-differentiated adenocarcinoma (1%), pulmonary chondroma (1%), and bronchiectasis (1%). Conclusion: The most common finding observed was pulmonary edema. In our study, male preponderance was noted. This study emphasizes to scrutinize the histopathological findings in the lung, especially following a sudden death.https://www.nepjol.info/index.php/AJMS/article/view/57717lung; autopsy; pulmonary edema; congestion |
| spellingShingle | Gowri Prakasam Brihadisvarar Sadasivam Vallabi Rajasekaran Kavitha Muniraj Abikarthiga Prathapan Histopathological spectrum of lung findings in autopsy cases Asian Journal of Medical Sciences lung; autopsy; pulmonary edema; congestion |
| title | Histopathological spectrum of lung findings in autopsy cases |
| title_full | Histopathological spectrum of lung findings in autopsy cases |
| title_fullStr | Histopathological spectrum of lung findings in autopsy cases |
| title_full_unstemmed | Histopathological spectrum of lung findings in autopsy cases |
| title_short | Histopathological spectrum of lung findings in autopsy cases |
| title_sort | histopathological spectrum of lung findings in autopsy cases |
| topic | lung; autopsy; pulmonary edema; congestion |
| url | https://www.nepjol.info/index.php/AJMS/article/view/57717 |
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