High Glucose Concentrations Impair the Processing and Presentation of <i>Mycobacterium tuberculosis</i> Antigens In Vitro

High Glucose Concentrations Impair the Processing and Presentation of <i>Mycobacterium tuberculosis</i> Antigens In Vitro

Type 2 diabetes is an established risk factor for tuberculosis, but the underlying mechanisms are largely unknown. We established an in vitro model to analyze the effect of high glucose concentrations in antigen processing and presentation in antigen-presenting cells. Human monocyte-derived macropha...

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Bibliographic Details
Main Authors:	Guadalupe Monroy-Mérida, Silvia Guzmán-Beltrán, Fernando Hernández, Teresa Santos-Mendoza, Karen Bobadilla
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Biomolecules
Subjects:	high glucose concentrations mycobacterium tuberculosis antigenic processing antigenic presentation CD4+ T cells
Online Access:	https://www.mdpi.com/2218-273X/11/12/1763

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