Extranodal NK/T-cell lymphoma: a review of literature and case report

Extranodal NK/T-cell lymphoma: a review of literature and case report

Extranodal NK/T-cell lymphoma – a rare lymphoproliferative disease characterized predominantly by extranodal localization, aggressive course and low efficiency of conventional chemotherapy. Clinical presentation is diverse and depends on tumor lesion localization. In this article, a literature revie...

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Bibliographic Details
Main Authors: N. G. Chernova, M. V. Nareyko, M. N. Sinitsyna, Yu. V. Sidorova, G. A. Yatsy, A. M. Kovrigina, E. E. Zvonkov, V. N. Dvirnyk, L. A. Kuz’mina, E. N. Parovichnikova, V. G. Savchenko
Format: Article
Language:Russian
Published: ABV-press 2016-10-01
Series:Онкогематология
Subjects:
extranodal nk/т-cell lymphoma
immunohistochemistry
clonal rearrangements
chemotherapy
allogeneic unrelated hematopoietic stem cell transplantation
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/204
Description
Summary:Extranodal NK/T-cell lymphoma – a rare lymphoproliferative disease characterized predominantly by extranodal localization, aggressive course and low efficiency of conventional chemotherapy. Clinical presentation is diverse and depends on tumor lesion localization. In this article, a literature review and case report of patient with generalized extranodal NK/T-cell lymphoma with bone marrow involvement, unusual intracranial tumor localization, tumor leukemization and central nervous system-leukemia were presented. Adequate treatment strategy made it possible to achieve long-term complete remission in a patient with poor prognosis.
ISSN:1818-8346
2413-4023

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