Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab
Yuqi Chu, Taoming Liu, Juan Bai, Hong Fang, Jianjun Qiao Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Jianjun Qiao, Department of Dermatology, The First Affiliated Hospital, Zhejiang University S...
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Format: | Article |
Language: | English |
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Dove Medical Press
2022-09-01
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Series: | Clinical, Cosmetic and Investigational Dermatology |
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Online Access: | https://www.dovepress.com/successful-treatment-of-a-patient-with-pyoderma-gangrenosum-plaque-pso-peer-reviewed-fulltext-article-CCID |
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author | Chu Y Liu T Bai J Fang H Qiao J |
author_facet | Chu Y Liu T Bai J Fang H Qiao J |
author_sort | Chu Y |
collection | DOAJ |
description | Yuqi Chu, Taoming Liu, Juan Bai, Hong Fang, Jianjun Qiao Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Jianjun Qiao, Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, 310003, People’s Republic of China, Tel +86 13735542393, Email qiaojianjun@zju.edu.cnAbstract: Pyoderma gangrenosum (PG) is a rare autoinflammatory skin disorder, which is characterised by rapidly developing and tender cutaneous ulcers. The treatment of PG is challenging. Palmoplantar pustulosis (PPP) is also an autoinflammatory dermatosis with sterile pustules on the palms and/or the soles. We demonstrated a 68-year-old patient with coexisting autoinflammatory diseases including PG, 1-year history of plaque psoriasis and PPP, recovered after treatment with adalimumab. We also reviewed published reports of PG-associated autoinflammatory syndromes with adalimumab.Keywords: adalimumab, autoinflammatory syndrome, palmoplantar pustulosis, plaque psoriasis, pyoderma gangrenosum |
first_indexed | 2024-04-14T08:21:12Z |
format | Article |
id | doaj.art-b06df3db0421466eb3a0387d546f78fc |
institution | Directory Open Access Journal |
issn | 1178-7015 |
language | English |
last_indexed | 2024-04-14T08:21:12Z |
publishDate | 2022-09-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Clinical, Cosmetic and Investigational Dermatology |
spelling | doaj.art-b06df3db0421466eb3a0387d546f78fc2022-12-22T02:04:13ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152022-09-01Volume 151991199578396Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with AdalimumabChu YLiu TBai JFang HQiao JYuqi Chu, Taoming Liu, Juan Bai, Hong Fang, Jianjun Qiao Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Jianjun Qiao, Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, 310003, People’s Republic of China, Tel +86 13735542393, Email qiaojianjun@zju.edu.cnAbstract: Pyoderma gangrenosum (PG) is a rare autoinflammatory skin disorder, which is characterised by rapidly developing and tender cutaneous ulcers. The treatment of PG is challenging. Palmoplantar pustulosis (PPP) is also an autoinflammatory dermatosis with sterile pustules on the palms and/or the soles. We demonstrated a 68-year-old patient with coexisting autoinflammatory diseases including PG, 1-year history of plaque psoriasis and PPP, recovered after treatment with adalimumab. We also reviewed published reports of PG-associated autoinflammatory syndromes with adalimumab.Keywords: adalimumab, autoinflammatory syndrome, palmoplantar pustulosis, plaque psoriasis, pyoderma gangrenosumhttps://www.dovepress.com/successful-treatment-of-a-patient-with-pyoderma-gangrenosum-plaque-pso-peer-reviewed-fulltext-article-CCIDadalimumabautoinflammatory syndromepalmoplantar pustulosisplaque psoriasispyoderma gangrenosum |
spellingShingle | Chu Y Liu T Bai J Fang H Qiao J Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab Clinical, Cosmetic and Investigational Dermatology adalimumab autoinflammatory syndrome palmoplantar pustulosis plaque psoriasis pyoderma gangrenosum |
title | Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab |
title_full | Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab |
title_fullStr | Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab |
title_full_unstemmed | Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab |
title_short | Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab |
title_sort | successful treatment of a patient with pyoderma gangrenosum plaque psoriasis and palmoplantar pustulosis with adalimumab |
topic | adalimumab autoinflammatory syndrome palmoplantar pustulosis plaque psoriasis pyoderma gangrenosum |
url | https://www.dovepress.com/successful-treatment-of-a-patient-with-pyoderma-gangrenosum-plaque-pso-peer-reviewed-fulltext-article-CCID |
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