Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab

Yuqi Chu, Taoming Liu, Juan Bai, Hong Fang, Jianjun Qiao Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Jianjun Qiao, Department of Dermatology, The First Affiliated Hospital, Zhejiang University S...

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Main Authors: Chu Y, Liu T, Bai J, Fang H, Qiao J
Format: Article
Language:English
Published: Dove Medical Press 2022-09-01
Series:Clinical, Cosmetic and Investigational Dermatology
Subjects:
Online Access:https://www.dovepress.com/successful-treatment-of-a-patient-with-pyoderma-gangrenosum-plaque-pso-peer-reviewed-fulltext-article-CCID
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author Chu Y
Liu T
Bai J
Fang H
Qiao J
author_facet Chu Y
Liu T
Bai J
Fang H
Qiao J
author_sort Chu Y
collection DOAJ
description Yuqi Chu, Taoming Liu, Juan Bai, Hong Fang, Jianjun Qiao Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Jianjun Qiao, Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, 310003, People’s Republic of China, Tel +86 13735542393, Email qiaojianjun@zju.edu.cnAbstract: Pyoderma gangrenosum (PG) is a rare autoinflammatory skin disorder, which is characterised by rapidly developing and tender cutaneous ulcers. The treatment of PG is challenging. Palmoplantar pustulosis (PPP) is also an autoinflammatory dermatosis with sterile pustules on the palms and/or the soles. We demonstrated a 68-year-old patient with coexisting autoinflammatory diseases including PG, 1-year history of plaque psoriasis and PPP, recovered after treatment with adalimumab. We also reviewed published reports of PG-associated autoinflammatory syndromes with adalimumab.Keywords: adalimumab, autoinflammatory syndrome, palmoplantar pustulosis, plaque psoriasis, pyoderma gangrenosum
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spelling doaj.art-b06df3db0421466eb3a0387d546f78fc2022-12-22T02:04:13ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152022-09-01Volume 151991199578396Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with AdalimumabChu YLiu TBai JFang HQiao JYuqi Chu, Taoming Liu, Juan Bai, Hong Fang, Jianjun Qiao Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Jianjun Qiao, Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, 310003, People’s Republic of China, Tel +86 13735542393, Email qiaojianjun@zju.edu.cnAbstract: Pyoderma gangrenosum (PG) is a rare autoinflammatory skin disorder, which is characterised by rapidly developing and tender cutaneous ulcers. The treatment of PG is challenging. Palmoplantar pustulosis (PPP) is also an autoinflammatory dermatosis with sterile pustules on the palms and/or the soles. We demonstrated a 68-year-old patient with coexisting autoinflammatory diseases including PG, 1-year history of plaque psoriasis and PPP, recovered after treatment with adalimumab. We also reviewed published reports of PG-associated autoinflammatory syndromes with adalimumab.Keywords: adalimumab, autoinflammatory syndrome, palmoplantar pustulosis, plaque psoriasis, pyoderma gangrenosumhttps://www.dovepress.com/successful-treatment-of-a-patient-with-pyoderma-gangrenosum-plaque-pso-peer-reviewed-fulltext-article-CCIDadalimumabautoinflammatory syndromepalmoplantar pustulosisplaque psoriasispyoderma gangrenosum
spellingShingle Chu Y
Liu T
Bai J
Fang H
Qiao J
Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab
Clinical, Cosmetic and Investigational Dermatology
adalimumab
autoinflammatory syndrome
palmoplantar pustulosis
plaque psoriasis
pyoderma gangrenosum
title Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab
title_full Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab
title_fullStr Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab
title_full_unstemmed Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab
title_short Successful Treatment of a Patient with Pyoderma Gangrenosum, Plaque Psoriasis and Palmoplantar Pustulosis with Adalimumab
title_sort successful treatment of a patient with pyoderma gangrenosum plaque psoriasis and palmoplantar pustulosis with adalimumab
topic adalimumab
autoinflammatory syndrome
palmoplantar pustulosis
plaque psoriasis
pyoderma gangrenosum
url https://www.dovepress.com/successful-treatment-of-a-patient-with-pyoderma-gangrenosum-plaque-pso-peer-reviewed-fulltext-article-CCID
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