Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis

Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF) is a chronically progressive interstitial lung that affects over 3 M people worldwide and rising in incidence. With a median survival of 2–3 years, IPF is consequently associated with high morbidity, mortality, and healthcare burden. Although two antifibrotic ther...

Full description

Bibliographic Details
Main Authors:	Melissa Skibba, Adam Drelich, Michael Poellmann, Seungpyo Hong, Allan R. Brasier
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-12-01
Series:	Frontiers in Pharmacology
Subjects:	fibrosis epigenetics (MeSH) nanomedicine epithelial mesenchymal transformation bromodomain-containing protein 4 lung
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2020.607689/full

Similar Items

Research progress of epigenetics in epilepsy
by: Wen-yue WU, et al.
Published: (2018-06-01)

NONINVASIVE PARAMETERS AND STAGING OF LIVER FIBROSIS IN CHRONIC HEPATITIS C PATIENTS
by: Abdur Rahim, et al.
Published: (2019-03-01)

Targeting inducible epigenetic reprogramming pathways in chronic airway remodeling
by: Allan R Brasier, et al.
Published: (2019-10-01)

Systematic review of catatonia treatment
by: Pelzer ACM, et al.
Published: (2018-01-01)

Macronutrients and Micronutrients in Parenteral Nutrition for Preterm Newborns: A Narrative Review
by: Valentina Rizzo, et al.
Published: (2022-04-01)

OUTCOME OF CHILDREN WITH RETINOBLASTOMA TREATED WITH PRIMARY CHEMOTHERAPY
by: Tariq Muhammad Saeed, et al.
Published: (2019-03-01)

ULTRASOUND GUIDED HYDROSTATIC REDUCTION OF INTUSSUSCEPTIONS IN CHILDREN WITH LATE PRESENTATION
by: Nadeem Ullah, et al.
Published: (2019-03-01)

Spraino: A novel low-friction device for prevention of lateral ankle sprain injuries in indoor sports
by: Filip Gertz Lysdal, et al.
Published: (2022-12-01)

Attitudes towards evaluation of psychiatric disability claims: a survey of Swiss stakeholders
by: Stefan Schandelmaier, et al.
Published: (2015-08-01)

Accuracy of Tools to Differentiate Single From Recurrent Fallers Pre-Frail Older Women
by: Tamires Terezinha Gallo da Silva, et al.
Published: (2022-05-01)

A multicomponent family support intervention in intensive care units: study protocol for a multicenter cluster-randomized trial (FICUS Trial)
by: Rahel Naef, et al.
Published: (2022-06-01)

Back pain and radicular pain after lumbar microdiscectomy
by: Konsta Koivunen, et al.
Published: (2023-07-01)

Association between intergenerational solidarity involving elders and mental health of Indigenous people living off reserve
by: Chantal Viscogliosi, et al.
Published: (2022-03-01)

Epigenetics Underlying Susceptibility and Resilience Relating to Daily Life Stress, Work Stress, and Socioeconomic Status
by: Michael G. Gottschalk, et al.
Published: (2020-03-01)

Neonatal outcomes in obese mothers: a population-based analysis
by: Minsart Anne-Frederique, et al.
Published: (2013-02-01)

RSV Reprograms the CDK9•BRD4 Chromatin Remodeling Complex to Couple Innate Inflammation to Airway Remodeling
by: Allan R. Brasier
Published: (2020-04-01)

Second opinion for degenerative spinal conditions: an option or a necessity? A prospective observational study
by: Mario Lenza, et al.
Published: (2017-08-01)

Nephrotoxic drug burden among 1001 critically ill patients: impact on acute kidney injury
by: Stephan Ehrmann, et al.
Published: (2019-09-01)

EFFECTS OF PROPHYLACTIC MATERNAL DEXAMETHASONE ADMINISTRATION ON THE NEONATAL RESPIRATORY OUTCOMES AT TERM AFTER ELECTIVE CAESAREAN SECTION: RANDOMIZED CONTROLLED TRIAL
by: Hasina Sadiq, et al.
Published: (2019-03-01)

Intramuscular Tendon Injuries of the Hamstring Muscles: A More Severe Variant? A Narrative Review
by: Fearghal Kerin, et al.
Published: (2023-08-01)

Identification of aspects of functioning, disability and health relevant to patients experiencing vertigo: a qualitative study using the international classification of functioning, disability and health
by: Mueller Martin, et al.
Published: (2012-06-01)

Research approvals iceberg: how a ‘low-key’ study in England needed 89 professionals to approve it and how we can do better
by: Mila Petrova, et al.
Published: (2019-01-01)

POSITIVE ATTITUDE AND STRESS AMONG ADULTS WITH CORONARY HEART DISEASES IN FAISALABAD
by: Syed Muhammad Imran Haider Zaidi, et al.
Published: (2018-09-01)

Response to Correspondence from Kolstoe and colleagues concerning our paper entitled, Research approvals iceberg: How a ‘low-key’ study in England needed 89 professionals to approve it and how we can do better
by: Mila Petrova, et al.
Published: (2019-12-01)

Study protocol: evaluation of specialized outpatient palliative care (SOPC) in the German state of Hesse (ELSAH study) – work package II: palliative care for pediatric patients
by: Lisa-R. Ulrich, et al.
Published: (2018-01-01)

Editorial: Adults with childhood onset disabilities: A lifespan approach
by: Elisabet Rodby-Bousquet, et al.
Published: (2023-01-01)

Outcomes in patients with chronic uveitis: which factors matter to patients? A qualitative study
by: Aline C. Stolk-Vos, et al.
Published: (2020-03-01)

Aislamientos bacterianos en apendicitis aguda
by: Maikel Adolfo Pacheco, et al.
Published: (2014-09-01)

Ability of functional performance assessments to discriminate athletes with and without chronic ankle instability : a case-control study
by: Madhura S. Jamsandekar, et al.
Published: (2022-05-01)

Mechanisms of Hamstring Strain Injury: Interactions between Fatigue, Muscle Activation and Function
by: Shaun Huygaerts, et al.
Published: (2020-05-01)

Physicians’ perspectives and future vision on disability assessments by phone during the COVID-19 pandemic: a cross-sectional survey
by: Nadia Baart, et al.
Published: (2022-05-01)

Trends of blood pressure and heart rate in normal pregnancies: a systematic review and meta-analysis
by: Lise Loerup, et al.
Published: (2019-09-01)

Searching for consensus among physicians involved in the management of sick-listed workers in the Belgian health care sector: a qualitative study among practitioners and stakeholders
by: Marc Vanmeerbeek, et al.
Published: (2016-02-01)

Relationship between the structure, function and endothelial damage, and vascular ageing and the biopsychological situation in adults diagnosed with persistent COVID (BioICOPER study). A research protocol of a cross-sectional study
by: Leticia Gómez-Sánchez, et al.
Published: (2023-09-01)

Elective surgical referral guidelines - background educational material or essential shared decision making tool? A survey of GPs' in England
by: Martin Steven, et al.
Published: (2011-08-01)

The perceived importance of prognostic aspects considered by physicians during work disability evaluation: a survey
by: Sylvia P. Snoeck-Krygsman, et al.
Published: (2022-01-01)

Integrating patient- and caregiver-reported outcome measures into the daily care routines of specialised outpatient palliative care: a qualitative study (ELSAH) on feasibility, acceptability and appropriateness
by: Hannah Seipp, et al.
Published: (2022-05-01)

Physician-staffed helicopter emergency medical service has a beneficial impact on the incidence of prehospital hypoxia and secured airways on patients with severe traumatic brain injury
by: Toni Pakkanen, et al.
Published: (2017-09-01)

FUNCTIONAL RECOVERY IN PATIENTS WITH POST-TRAUMATIC SPINAL CORD INJURIES: AN OUTCOME OF GROSS MOBILITY AT PARAPLEGIC CENTER PESHAWAR, PAKISTAN
by: Amir Zeb, et al.
Published: (2019-03-01)

CAUSES OF LOWER LIMB AMPUTATION IN PATIENTS REGISTERED AT PAKISTAN INSTITUTE OF PROSTHETIC AND ORTHOTIC SCIENCES PESHAWAR-PAKISTAN
by: Aziz Ahmad, et al.
Published: (2019-03-01)