A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemia
Tyrosine kinase inhibitors (TKIs) have significantly improved the prognosis of chronic myeloid leukemia (CML) since their approval. Although safe in general, TKIs carry concerns about cardiovascular adverse events. Hypertension, diabetes, and dyslipidemia are among the most common baseline comorbidi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.1025392/full |
| _version_ | 1811301082621542400 |
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| author | Khalid Ahmed Rasha Kaddoura Mohamed A. Yassin |
| author_facet | Khalid Ahmed Rasha Kaddoura Mohamed A. Yassin |
| author_sort | Khalid Ahmed |
| collection | DOAJ |
| description | Tyrosine kinase inhibitors (TKIs) have significantly improved the prognosis of chronic myeloid leukemia (CML) since their approval. Although safe in general, TKIs carry concerns about cardiovascular adverse events. Hypertension, diabetes, and dyslipidemia are among the most common baseline comorbidities among CML patients. Guidelines for the management of the existing comorbidities or those related to TKI therapy are lacking. This paper will review hypertension, hyperglycemia and hyperlipidemia reported in CML patients or associated with TKI therapy and then propose a simple guide on their management. |
| first_indexed | 2024-04-13T07:02:26Z |
| format | Article |
| id | doaj.art-b076c7c98d0041a48446e724ee18dc91 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-13T07:02:26Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-b076c7c98d0041a48446e724ee18dc912022-12-22T02:57:05ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-12-01910.3389/fmed.2022.10253921025392A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemiaKhalid Ahmed0Rasha Kaddoura1Mohamed A. Yassin2Department of Hematology, National Center for Cancer Care and Research (NCCCR), Hamad Medical Corporation (HMC), Doha, QatarPharmacy Department, Heart Hospital, Hamad Medical Corporation (HMC), Doha, QatarDepartment of Hematology, National Center for Cancer Care and Research (NCCCR), Hamad Medical Corporation (HMC), Doha, QatarTyrosine kinase inhibitors (TKIs) have significantly improved the prognosis of chronic myeloid leukemia (CML) since their approval. Although safe in general, TKIs carry concerns about cardiovascular adverse events. Hypertension, diabetes, and dyslipidemia are among the most common baseline comorbidities among CML patients. Guidelines for the management of the existing comorbidities or those related to TKI therapy are lacking. This paper will review hypertension, hyperglycemia and hyperlipidemia reported in CML patients or associated with TKI therapy and then propose a simple guide on their management.https://www.frontiersin.org/articles/10.3389/fmed.2022.1025392/fullchronic myeloid leukemiahypertensionhyperglycemiahyperlipidemiadasatinibnilotinib |
| spellingShingle | Khalid Ahmed Rasha Kaddoura Mohamed A. Yassin A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemia Frontiers in Medicine chronic myeloid leukemia hypertension hyperglycemia hyperlipidemia dasatinib nilotinib |
| title | A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemia |
| title_full | A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemia |
| title_fullStr | A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemia |
| title_full_unstemmed | A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemia |
| title_short | A practical guide to managing hypertension, hyperlipidemia, and hyperglycemia in patients with chronic myeloid leukemia |
| title_sort | practical guide to managing hypertension hyperlipidemia and hyperglycemia in patients with chronic myeloid leukemia |
| topic | chronic myeloid leukemia hypertension hyperglycemia hyperlipidemia dasatinib nilotinib |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.1025392/full |
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