Meeting an un-MET need: Targeting MET in non-small cell lung cancer
The MET pathway can be activated by MET exon 14 skipping mutations, gene amplification, or overexpression. Mutations within this pathway carry a poor prognosis for patients with non-small cell lung cancer (NSCLC). MET exon 14 skipping mutations occur in 3-4% of patients with NSCLC, while MET amplifi...
Autores principales: | , |
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Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022-10-01
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Colección: | Frontiers in Oncology |
Materias: | |
Acceso en línea: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1004198/full |