Meeting an un-MET need: Targeting MET in non-small cell lung cancer

The MET pathway can be activated by MET exon 14 skipping mutations, gene amplification, or overexpression. Mutations within this pathway carry a poor prognosis for patients with non-small cell lung cancer (NSCLC). MET exon 14 skipping mutations occur in 3-4% of patients with NSCLC, while MET amplifi...

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Detalles Bibliográficos
Main Authors: Elena Michaels, Christine M. Bestvina
Formato: Artigo
Idioma:English
Publicado: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2022.1004198/full